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| Content Provider | PubMed Central |
|---|---|
| Author | Park, Sungsu Wolanin, Peter M. Yuzbashyan, Emil A. Lin, Hai Darnton, Nicholas C. Stock, Jeffry B. Pascal, Silberzan Austin, Robert |
| Copyright Year | 2003 |
| Abstract | The environmental topology of complex structures is used by Escherichia coli to create traveling waves of high cell density, a prelude to quorum sensing. When cells are grown to a moderate density within a confining microenvironment, these traveling waves of cell density allow the cells to find and collapse into confining topologies, which are unstable to population fluctuations above a critical threshold. This was first observed in mazes designed to mimic complex environments, then more clearly in a simpler geometry consisting of a large open area surrounding a square (250 × 250 μm) with a narrow opening of 10–30 μm. Our results thus show that under nutrient-deprived conditions bacteria search out each other in a collective manner and that the bacteria can dynamically confine themselves to highly enclosed spaces. |
| Related Links | http://dx.doi.org/10.1073/pnas.1935975100 |
| Ending Page | 13915 |
| Page Count | 6 |
| Starting Page | 13910 |
| File Format | |
| ISSN | 00278424 |
| e-ISSN | 10916490 |
| Journal | Proceedings of the National Academy of Sciences of the United States of America |
| Issue Number | 24 |
| Volume Number | 100 |
| Language | English |
| Publisher | National Academy of Sciences |
| Publisher Date | 2003-11-25 |
| Access Restriction | Open |
| Rights Holder | National Academy of Sciences |
| Subject Keyword | General Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Multidisciplinary |
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