NDLI: Investigation of the feasibility of relative 3D dosimetry in the Radiologic Physics Center Head and Neck IMRT phantom using Presage/optical-CT

Content Provider	PubMed Central
Author	Sakhalkar, Harshad Sterling, David John, Adamovics Ibbott, Geoffrey Oldham, Mark
Copyright Year	2009
Abstract	This study presents the application of the Presage∕optical-CT 3D dosimetry system for relative dosimetry in the Radiologic Physics Center (RPC) Head and Neck (H&N) IMRT phantom. Performance of the system was evaluated by comparison with the “gold-standard” RPC credentialing test. A modified Presage cylindrical insert was created that extended the capability of the RPC H&N phantom to 3D dosimetry. The RPC phantom was taken through the entire treatment planning procedure with both the standard RPC insert and the modified Presage insert. An IMRT plan was created to match the desired dose constraints of the credentialing test. This plan was delivered twice to the RPC phantom: first containing the standard insert, and then again containing the Presage insert. After irradiation, the standard insert was sent for routine credentialing analysis; including point dose measurements (TLD) and planar Gafchromic® EBT film measurement. The 3D dose distribution from Presage was read out at Duke using the OCTOPUS™ 5X optical-CT scanner. The Presage distribution was compared with gold-standard EBT measurement (determined by the RPC) and the calculated Eclipse distribution. The agreement between the normalized EBT, Presage, and Eclipse distributions, in the central axial plane was evaluated using profiles and gamma-map comparisons (4% dose difference and 3 mm distance to agreement). Profiles showed good agreement between EBT, Presage, and Eclipse distributions. 2D gamma-map comparisons between all three modalities showed at least 98% pass rate. The excellent agreement between Presage and EBT in the central plane established Presage as a standard against which to evaluate the accuracy of the 3D calculated Eclipse distribution. A gamma comparison between normalized Presage and Eclipse 3D distributions gave an overall pass rate of ∼94%. In conclusion, the Presage∕optical-CT system was found to be feasible for relative 3D dosimetry in the RPC IMRT H&N phantom. The potential to extend the RPC IMRT credentialing procedure to 3D may be feasible provided accurate calibration to dose (Gy) and robustness to shipping stress are demonstrated.
Related Links	http://dx.doi.org/10.1118/1.3148534
Starting Page	3371
File Format	PDF
ISSN	00942405
e-ISSN	00942405
Journal	Medical Physics
Issue Number	7
Volume Number	36
Language	English
Publisher	American Association of Physicists in Medicine
Publisher Date	2009-01-01
Access Restriction	Open
Rights Holder	American Association of Physicists in Medicine
Subject Keyword	Biophysics Radiology Nuclear Medicine and imaging Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Radiology, Nuclear Medicine and Imaging Biophysics

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1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
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4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
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