NDLI: Negative regulation of DNA synthesis in early erythropoietic progenitor cells (BFU-E) by a protein purified from the medium of C57BL/6 mouse marrow cells.

Please wait, while we are loading the content...

Year: 2016, Volume: 113

Year: 2015, Volume: 112

Year: 2014, Volume: 111

Year: 2013, Volume: 110

Year: 2012, Volume: 109

Year: 2011, Volume: 109

Year: 2011, Volume: 108

Year: 2010, Volume: 107

Year: 2009, Volume: 106

Year: 2009, Volume: 94

Year: 2008, Volume: 105

Year: 2007, Volume: 104

Year: 2006, Volume: 103

Year: 2005, Volume: 103

Year: 2005, Volume: 102

Year: 2004, Volume: 101

Year: 2003, Volume: 100

Year: 2002, Volume: 99

Year: 2001, Volume: 98

Year: 2000, Volume: 97

Year: 1999, Volume: 96

Year: 1998, Volume: 95

Year: 1997, Volume: 94

Year: 1996, Volume: 93

Year: 1995, Volume: 92

Year: 1994, Volume: 91

Year: 1993, Volume: 90

Year: 1992, Volume: 89

Year: 1991, Volume: 88

Year: 1990, Volume: 87

Year: 1989, Volume: 86

Year: 1988, Volume: 85

Year: 1988, Volume: 85, Issue: Suppl

Year: 1988, Volume: 85, Issue: 24

Year: 1988, Volume: 85, Issue: 23

Year: 1988, Volume: 85, Issue: 22

Year: 1988, Volume: 85, Issue: 21

Year: 1988, Volume: 85, Issue: 20

Year: 1988, Volume: 85, Issue: 19

Year: 1988, Volume: 85, Issue: 18

Year: 1988, Volume: 85, Issue: 17

Year: 1988, Volume: 85, Issue: 16

Year: 1988, Volume: 85, Issue: 15

Year: 1988, Volume: 85, Issue: 14

Year: 1988, Volume: 85, Issue: 13

Year: 1988, Volume: 85, Issue: 12

High-resolution 13C NMR study of pressure effects on the main phase transition in L-alpha-dipalmitoyl phosphatidylcholine vesicles.

Crystal and molecular structure of didemnin B, an antiviral and cytotoxic depsipeptide.

A histone H1 protein in sea urchins is encoded by a poly(A)+ mRNA.

2,3,7,8-Tetrachlorodibenzo-p-dioxin causes increases in expression of c-erb-A and levels of protein-tyrosine kinases in selected tissues of responsive mouse strains.

Structure of chloramphenicol acetyltransferase at 1.75-A resolution.

Cooperative DNA binding of heterologous proteins: evidence for contact between the cyclic AMP receptor protein and RNA polymerase.

Altered regulation of lipid biosynthesis in a mutant of Arabidopsis deficient in chloroplast glycerol-3-phosphate acyltransferase activity

Aspartic acid substitutions affect proton translocation by bacteriorhodopsin.

Identification of cDNA encoding an additional alpha subunit of a human GTP-binding protein: expression of three alpha i subtypes in human tissues and cell lines.

The major adduct of the antitumor drug cis-diamminedichloroplatinum(II) with DNA bends the duplex by approximately equal to 40 degrees toward the major groove.

Mutant 16S ribosomal RNA: a codon-specific translational suppressor.

Isolation of a Bacillus thuringiensis RNA polymerase capable of transcribing crystal protein genes.

Adenoviral control regions activated by E1A and the cAMP response element bind to the same factor.

Putative structure and functions of a poly-beta-hydroxybutyrate/calcium polyphosphate channel in bacterial plasma membranes.

Putative metabolites derived from dietary combinations of calcium glucarate and N-(4-hydroxyphenyl)retinamide act synergistically to inhibit the induction of rat mammary tumors by 7,12-dimethylbenz[a]anthracene.

Synthetic peptides as substrates and inhibitors of a retroviral protease.

mRNAs encoding ribulose-1,5-bisphosphate carboxylase remain bound to polysomes but are not translated in amaranth seedlings transferred to darkness

Characterization of a zinc blotting technique: evidence that a retroviral gag protein binds zinc.

Trans-activation of the human immunodeficiency virus long terminal repeat sequences, expressed in an adenovirus vector, by the adenovirus E1A 13S protein.

Three-dimensional structure of carbamoyl phosphate and succinate bound to aspartate carbamoyltransferase.

Transcription of oxygen-regulated photosynthetic genes requires DNA gyrase in Rhodobacter capsulatus.

Primary structure of the human follistatin precursor and its genomic organization.

Evidence for a cAMP-dependent nuclear factor capable of interacting with a specific region of a eukaryotic gene.

A beta-cell-specific protein binds to the two major regulatory sequences of the insulin gene enhancer.

Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation.

Escherichia coli host factor for site-specific DNA inversion: cloning and characterization of the fis gene.

Codon choice and gene expression: synonymous codons differ in their ability to direct aminoacylated-transfer RNA binding to ribosomes in vitro.

Mutation of a site of tyrosine phosphorylation in the lymphocyte-specific tyrosine protein kinase, p56lck, reveals its oncogenic potential in fibroblasts.

Human liver phosphatase 2A: cDNA and amino acid sequence of two catalytic subunit isotypes.

Avian reovirus mRNAs are nonfunctional in infected mouse cells: translational basis for virus host-range restriction.

No strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene.

Stress proteins are immune targets in leprosy and tuberculosis.

Malignant transformation by ras and other oncogenes produces common alterations in inositol phospholipid signaling pathways.

Use of site-directed mutagenesis to elucidate the role of arginine-166 in the catalytic mechanism of alkaline phosphatase.

Detection of activated double-stranded RNA-dependent protein kinase in 3T3-F442A cells

Probing the salt bridge in the dihydrofolate reductase-methotrexate complex by using the coordinate-coupled free-energy perturbation method.

Regulation of the surface pressure of lipid monolayers and bilayers by the activity of water: derivation and application of an equation of state.

Purified skeletal muscle 1,4-dihydropyridine receptor forms phosphorylation-dependent oligomeric calcium channels in planar bilayers.

Energetics of the structure of the four-alpha-helix bundle in proteins.

A stable bifunctional antisense transcript inhibiting gene expression in transgenic plants

Transfer of foreign genes into intact maize cells with high-velocity microprojectiles

An enhancer-like element present in the promoter of a T-DNA gene from the Ti plasmid of Agrobacterium tumefaciens

Small ribonucleoproteins in Schizosaccharomyces pombe and Yarrowia lipolytica homologous to signal recognition particle.

Negative regulation of DNA synthesis in early erythropoietic progenitor cells (BFU-E) by a protein purified from the medium of C57BL/6 mouse marrow cells.

Heterotypic and homotypic associations between the nuclear lamins: site-specificity and control by phosphorylation.

Kinetics of gamma interferon binding and induction of major histocompatibility complex class II mRNA in Leishmania-infected macrophages.

Use of a mutant cell line to study the kinetics and function of O-linked glycosylation of low density lipoprotein receptors.

Control of pollen hydration in Brassica requires continued protein synthesis, and glycosylation in necessary for intraspecific incompatibility

NIH-3T3 cells transformed by the EJ-ras oncogene exhibit reduced platelet-derived growth factor-mediated Ca2+ mobilization.

The gene encoding multidrug resistance is induced and expressed at high levels during pregnancy in the secretory epithelium of the uterus.

Oncogene v-src transforms and establishes embryonic rodent fibroblasts but not diploid human fibroblasts.

Analysis in serum-free culture of the targets of recombinant human hemopoietic growth factors: interleukin 3 and granulocyte/macrophage-colony-stimulating factor are specific for early developmental stages.

Production of oxidative DNA damage during the metabolic activation of benzo[a]pyrene in human mammary epithelial cells correlates with cell killing.

Extracellular control of spore formation in Bacillus subtilis.

Social plasticity and early-diapausing females in a primitively social bee

Codon preference is but an illusion created by the construction principle of coding sequences.

Evolution of competitive ability in Drosophila by density-dependent natural selection.

Water-borne stimuli released by predatory crabs and damaged prey induce more predator-resistant shells in a marine gastropod

A cDNA encoding tyrosinase-related protein maps to the brown locus in mouse.

Reactivity of cytosine and thymine in single-base-pair mismatches with hydroxylamine and osmium tetroxide and its application to the study of mutations.

Specific insertion and deletion of insertion sequence 1-like DNA element causes the reversible expression of the virulence capsular antigen Vi of Citrobacter freundii in Escherichia coli.

DNA base sequence changes and sequence specificity of bromodeoxyuridine-induced mutations in mammalian cells.

Site-specific binding of viral plus single-stranded RNA to replicase-containing open virus-like particles of yeast.

Rat L (long interspersed repeated DNA) elements contain guanine-rich homopurine sequences that induce unpairing of contiguous duplex DNA.

Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit.

Dominant negative protein kinase mutations that confer a G1 arrest phenotype.

Structural analysis of the 5' flanking region of the beta-globin gene in African sickle cell anemia patients: further evidence for three origins of the sickle cell mutation in Africa.

Characterization of frequent deletions causing steroid 21-hydroxylase deficiency.

Recognition of galactosylgloboside by monoclonal antibodies derived from patients with primary lung cancer.

Differential ability of B cells specific for external vs. internal influenza virus proteins to respond to help from influenza virus-specific T-cell clones in vivo.

Infection of rabbit T-cell and macrophage lines with human immunodeficiency virus.

Protective immunity and eosinophilia in IgE-deficient SJA/9 mice infected with Nippostrongylus brasiliensis and Trichinella spiralis.

Reversal of the metastatic phenotype in Lewis lung carcinoma cells after transfection with syngeneic H-2Kb gene.

Regulation of interleukin 2 receptor alpha subunit (Tac or CD25 antigen) gene expression: binding of inducible nuclear proteins to discrete promoter sequences correlates with transcriptional activation.

Differentiation of an interleukin 3-dependent precursor B-cell clone into immunoglobulin-producing cells in vitro.

Human immunodeficiency virus type 1 neutralization epitope with conserved architecture elicits early type-specific antibodies in experimentally infected chimpanzees.

Endogenous adenosine and hemorrhagic shock: effects of caffeine administration or caffeine withdrawal.

A retrovirus carrying an MDR1 cDNA confers multidrug resistance and polarized expression of P-glycoprotein in MDCK cells.

Immunological identification of a high molecular weight protein as a candidate for the product of the Duchenne muscular dystrophy gene.

Three-dimensional model of the capsid proteins of two biologically different Theiler virus strains: clustering of amino acid difference identifies possible locations of immunogenic sites on the virion.

Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases.

Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease.

Increased prostacyclin and thromboxane A2 biosynthesis in atherosclerosis.

Renal autoimmune epitope of group A streptococci specified by M protein tetrapeptide Ile-Arg-Leu-Arg.

High levels of heterodisperse RNAs accumulate in T cells infected with human immunodeficiency virus and in normal thymocytes.

Human and bovine coronaviruses recognize sialic acid-containing receptors similar to those of influenza C viruses.

Neurofilament and tubulin expression recapitulates the developmental program during axonal regeneration: induction of a specific beta-tubulin isotype.

Background light and the contrast gain of primate P and M retinal ganglion cells.

VAMP-1: a synaptic vesicle-associated integral membrane protein.

Thy-1-mediated regulation of a low-threshold transient calcium current in cultured sensory neurons.

Ion transport by the Na-Ca exchange in isolated rod outer segments.

Beta 2-adrenergic mechanisms in experimental arthritis.

Dual effects of serotonin on a voltage-gated conductance in lymphocytes.

Rapid desensitization of glutamate receptors in vertebrate central neurons.

D1-type dopamine receptors inhibit growth cone motility in cultured retina neurons: evidence that neurotransmitters act as morphogenic growth regulators in the developing central nervous system.

Collective cues as a basis for nestmate recognition in polygynous leptothoracine ants

Year: 1988, Volume: 85, Issue: 11

Year: 1988, Volume: 85, Issue: 10

Year: 1988, Volume: 85, Issue: 9

Year: 1988, Volume: 85, Issue: 8

Year: 1988, Volume: 85, Issue: 7

Year: 1988, Volume: 85, Issue: 6

Year: 1988, Volume: 85, Issue: 5

Year: 1988, Volume: 85, Issue: 4

Year: 1988, Volume: 85, Issue: 3

Year: 1988, Volume: 85, Issue: 2

Year: 1988, Volume: 85, Issue: 1

Year: 1987, Volume: 84

Year: 1986, Volume: 83

Year: 1985, Volume: 82

Year: 1984, Volume: 81

Year: 1983, Volume: 80

Year: 1982, Volume: 79

Year: 1981, Volume: 78

Year: 1980, Volume: 77

Year: 1979, Volume: 76

Year: 1978, Volume: 75

Year: 1977, Volume: 74

Year: 1976, Volume: 73

Year: 1975, Volume: 72

Year: 1974, Volume: 71

Year: 1973, Volume: 70

Year: 1972, Volume: 69

Year: 1971, Volume: 68

Year: 1970, Volume: 67

Year: 1970, Volume: 66

Year: 1970, Volume: 65

Year: 1969, Volume: 64

Year: 1969, Volume: 63

Year: 1969, Volume: 62

Year: 1968, Volume: 61

Year: 1968, Volume: 60

Year: 1968, Volume: 59

Year: 1967, Volume: 58

Year: 1967, Volume: 57

Year: 1966, Volume: 56

Year: 1966, Volume: 55

Year: 1965, Volume: 54

Year: 1965, Volume: 53

Year: 1964, Volume: 52

Year: 1964, Volume: 51

Year: 1963, Volume: 50

Year: 1963, Volume: 49

Year: 1962, Volume: 48

Year: 1961, Volume: 47

Year: 1960, Volume: 46

Year: 1959, Volume: 45

Year: 1958, Volume: 44

Year: 1957, Volume: 43

Year: 1956, Volume: 42

Year: 1955, Volume: 41

Year: 1954, Volume: 40

Year: 1953, Volume: 39

Year: 1952, Volume: 38

Year: 1951, Volume: 37

Year: 1950, Volume: 36

Year: 1949, Volume: 35

Year: 1948, Volume: 34

Year: 1947, Volume: 33

Year: 1946, Volume: 32

Year: 1945, Volume: 31

Year: 1944, Volume: 30

Year: 1943, Volume: 29

Year: 1942, Volume: 28

Year: 1941, Volume: 27

Year: 1940, Volume: 26

Year: 1939, Volume: 25

Year: 1938, Volume: 24

Year: 1937, Volume: 23

Year: 1936, Volume: 22

Year: 1935, Volume: 21

Year: 1934, Volume: 20

Year: 1933, Volume: 19

Year: 1932, Volume: 18

Year: 1931, Volume: 17

Year: 1930, Volume: 16

Year: 1929, Volume: 15

Year: 1928, Volume: 14

Year: 1927, Volume: 13

Year: 1926, Volume: 12

Year: 1925, Volume: 11

Year: 1924, Volume: 10

Year: 1923, Volume: 9

Year: 1922, Volume: 8

Year: 1921, Volume: 7

Year: 1920, Volume: 6

Year: 1919, Volume: 5

Year: 1918, Volume: 4

Year: 1917, Volume: 3

Year: 1916, Volume: 2

Year: 1915, Volume: 1

Negative regulation of DNA synthesis in early erythropoietic progenitor cells (BFU-E) by a protein purified from the medium of C57BL/6 mouse marrow cells.

Content Provider	PubMed Central
Author	Rizzo, D. F. Del Eskinazi, D. Axelrad, A. A.
Abstract	During studies on the influence of Fv-2 on the cycle state of the erythroid burst-forming unit (BFU-E), an activity was found in bone marrow supernatants from C57BL/6 (B6) mice that shut down DNA synthesis of the BFU-E in vitro. It acted within minutes, its action was completely reversed by a single wash, and it appeared specific to the BFU-E. The activity-causing substance, being macromolecular, heat stable, and trypsin-sensitive, was evidently a protein and was named negative regulatory protein. We purified a negative regulatory protein from a bone marrow-derived "B6 Pan" cell line with properties thus far indistinguishable from those of the negative regulatory protein obtained directly from B6 marrow. By gel filtration the protein has a Mr of approximately equal to 79,000, by cation- and anion-exchange chromatography it appears to be a neutral molecule at physiological pH, and the molecule does not bind to Con A. After five sequential chromatographic steps, we obtained a preparation active at a concentration of 25 ng/ml. Our findings are compatible with the hypothesis that quiescence of BFU-E with respect to DNA synthesis in vivo in B6 mice is mediated by negative regulatory protein molecules.
Starting Page	4320
File Format	PDF
ISSN	10916490
e-ISSN	10916490
Journal	Proceedings of the National Academy of Sciences of the United States of America
Issue Number	12
Volume Number	85
Language	English
Publisher Date	1988-06-01
Access Restriction	Open
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Multidisciplinary

Central Library (ISO-9001:2015 Certified)
Indian Institute of Technology Kharagpur
Kharagpur, West Bengal, India | PIN - 721302

See location in the Map
03222 282435
Mail: support@ndl.gov.in

Sl.	Authority	Responsibilities	Communication Details
1	Ministry of Education (GoI), Department of Higher Education	Sanctioning Authority	https://www.education.gov.in/ict-initiatives
2	Indian Institute of Technology Kharagpur	Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project	https://www.iitkgp.ac.in
3	National Digital Library of India Office, Indian Institute of Technology Kharagpur	The administrative and infrastructural headquarters of the project	Dr. B. Sutradhar bsutra@ndl.gov.in
4	Project PI / Joint PI	Principal Investigator and Joint Principal Investigators of the project	Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon
5	Website/Portal (Helpdesk)	Queries regarding NDLI and its services	support@ndl.gov.in
6	Contents and Copyright Issues	Queries related to content curation and copyright issues	content@ndl.gov.in
7	National Digital Library of India Club (NDLI Club)	Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach	clubsupport@ndl.gov.in
8	Digital Preservation Centre (DPC)	Assistance with digitizing and archiving copyright-free printed books	dpc@ndl.gov.in
9	IDR Setup or Support	Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops	idr@ndl.gov.in