NDLI: Subclinical atherosclerosis: what it is, what it means and what we can do about it

Content Provider	PubMed Central
Author	Toth, P. P.
Copyright Year	2008
Abstract	Atherosclerosis is a chronic, progressive, inflammatory disease with a long asymptomatic phase. Disease progression can lead eventually to the occurrence of acute cardiovascular events such as myocardial infarction, unstable angina pectoris and sudden cardiac death. While the disease is still in a subclinical stage, however, the presence of atherosclerosis can be identified by several methods, including coronary angiography, intravascular ultrasonography, B-mode ultrasonography, computed tomography and magnetic resonance imaging. Based on the results of imaging studies, statin therapy can slow, halt or even reverse the progression of atherosclerotic disease, depending on the intensity of treatment. Whether to screen and treat patients for subclinical atherosclerosis remains controversial. Although atheromatous plaque burden reduction has not yet been definitively correlated with significant decreases in risk for acute coronary events in asymptomatic patients, statin therapy contributes significantly to the risk reduction observed in clinical trials in patients with and without overt coronary disease.
Related Links	http://dx.doi.org/10.1111/j.1742-1241.2008.01804.x
Ending Page	1254
Page Count	9
Starting Page	1246
File Format	PDF
ISSN	13685031
e-ISSN	17421241
Journal	International Journal of Clinical Practice
Issue Number	8
Volume Number	62
Language	English
Publisher	Blackwell Publishing Ltd
Publisher Date	2008-06-01
Access Restriction	Open
Rights Holder	Blackwell Publishing Ltd
Subject Keyword	Medicine(all) Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Medicine

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