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| Content Provider | PubMed Central |
|---|---|
| Author | Wilson, Kitchener Yu, Jin Lee, Andrew Wu, Joseph C. |
| Copyright Year | 2008 |
| Abstract | The discovery of human embryonic stem cells (hESCs) has dramatically increased the tools available to medical scientists interested in regenerative medicine. However, direct injection of hESCs, and cells differentiated from hESCs, into living organisms has thus far been hampered by significant cell death, teratoma formation, and host immune rejection. Understanding the in vivo hESC behavior after transplantation requires novel imaging techniques to longitudinally monitor hESC localization, proliferation, and viability. Molecular imaging has given investigators a high-throughput, inexpensive, and sensitive means for tracking in vivo cell proliferation over days, weeks, and even months. This advancement has significantly increased the understanding of the spatio-temporal kinetics of hESC engraftment, proliferation, and teratoma-formation in living subjects. |
| Related Links | http://dx.doi.org/10.3791/740 |
| Starting Page | 740 |
| File Format | |
| ISSN | 1940087X |
| e-ISSN | 1940087X |
| Journal | Journal of Visualized Experiments : JoVE |
| Issue Number | 14 |
| Language | English |
| Publisher | MyJove Corporation |
| Publisher Date | 2008-05-01 |
| Access Restriction | Open |
| Rights Holder | MyJove Corporation |
| Subject Keyword | Biochemistry, Genetics and Molecular Biology(all) Immunology and Microbiology(all) Chemical Engineering(all) Neuroscience(all) Medicine(all) Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Neuroscience Immunology and Microbiology Biochemistry, Genetics and Molecular Biology Chemical Engineering |
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