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| Content Provider | PubMed Central |
|---|---|
| Author | Okubadejo, Njideka Britton, Angela Crews, Cynthia Akinyemi, Rufus Hardy, John Singleton, Andrew Bras, Jose |
| Editor | Toland, Amanda Ewart |
| Copyright Year | 2008 |
| Abstract | Several genetic variations have been associated with Parkinson disease in different populations over the past few years. Although a considerable number of worldwide populations have been screened for these variants, results from Sub-Saharan populations are very scarce in the literature. In the present report we have screened a cohort of Parkinson disease patients (n = 57) and healthy controls (n = 51) from Nigeria for mutations in the genes PRKN, LRRK2 and ATXN3. No pathogenic mutations were found in any of the genes. Hence, common pathogenic mutations in these genes, observed in several different populations, are not a frequent cause of Parkinson disease in Nigeria. |
| Related Links | http://dx.doi.org/10.1371/journal.pone.0003421 |
| Starting Page | 3421 |
| File Format | |
| ISSN | 19326203 |
| e-ISSN | 19326203 |
| Journal | PLoS ONE |
| Issue Number | 10 |
| Volume Number | 3 |
| Language | English |
| Publisher | Public Library of Science |
| Publisher Date | 2008-10-01 |
| Access Restriction | Open |
| Rights Holder | Public Library of Science |
| Subject Keyword | Biochemistry, Genetics and Molecular Biology(all) Agricultural and Biological Sciences(all) Medicine(all) Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Multidisciplinary |
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