NDLI: Packaging of hepatitis delta virus RNA via the RNA-binding domain of hepatitis delta antigens: different roles for the small and large delta antigens.

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Visna virus Tat protein: a potent transcription factor with both activator and suppressor domains.

Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses.

Localization of the Vpx packaging signal within the C terminus of the human immunodeficiency virus type 2 Gag precursor protein.

Transcription of the human T-cell lymphotropic virus type I promoter by an alpha-amanitin-resistant polymerase.

Transrepression of RNA polymerase II promoters by the simian virus 40 small t antigen.

The EBNA-2 arginine-glycine domain is critical but not essential for B-lymphocyte growth transformation; the rest of region 3 lacks essential interactive domains.

Effects of alterations of primer-binding site sequences on human immunodeficiency virus type 1 replication.

Cleavage of p15 protein in vitro by human immunodeficiency virus type 1 protease is RNA dependent.

Two hepatitis C virus glycoprotein E2 products with different C termini.

Transactivation by the human cytomegalovirus IE2 86-kilodalton protein requires a domain that binds to both the TATA box-binding protein and the retinoblastoma protein.

The VBP and a1/EBP leucine zipper factors bind overlapping subsets of avian retroviral long terminal repeat CCAAT/enhancer elements.

Peripheral blood mononuclear phagocytes mediate dissemination of murine cytomegalovirus.

Use of a mammalian internal ribosomal entry site element for expression of a foreign protein by a transfectant influenza virus.

Cross-reactivity of anti-human immunodeficiency virus type 1 gp41 antibodies with human astrocytes and astrocytoma cell lines.

Monocyte maturation controls expression of equine infectious anemia virus.

Identification of latency-associated transcripts that map antisense to the ICP4 homolog gene of Marek's disease virus.

Semliki Forest virus infects mouse brain endothelial cells and causes blood-brain barrier damage.

Binding of measles virus to membrane cofactor protein (CD46): importance of disulfide bonds and N-glycans for the receptor function.

Biphasic viremia and viral gene expression in leukocytes during acute cytomegalovirus infection of mice.

Effect of mutations downstream of the internal ribosome entry site on initiation of poliovirus protein synthesis.

Induction of antibody responses that neutralize human T-cell leukemia virus type I infection in vitro and in vivo by peptide immunization.

Involvement of human leukocyte antigen class I molecules in human immunodeficiency virus infection of CD4-positive cells.

Identification of human immunodeficiency virus type 1 envelope genes recombinant between subtypes B and F in two epidemiologically linked individuals from Brazil.

Improved cell survival by the reduction of immediate-early gene expression in replication-defective mutants of herpes simplex virus type 1 but not by mutation of the virion host shutoff function.

Packaging of hepatitis delta virus RNA via the RNA-binding domain of hepatitis delta antigens: different roles for the small and large delta antigens.

Intracellular transport of newly synthesized varicella-zoster virus: final envelopment in the trans-Golgi network.

Intravaginal inoculation of rhesus macaques with cell-free simian immunodeficiency virus results in persistent or transient viremia.

Conditional lethal expression of the vaccinia virus L1R myristylated protein reveals a role in virion assembly.

The human papillomavirus type 16 E2 transcription factor binds with low cooperativity to two flanking sites and represses the E6 promoter through displacement of Sp1 and TFIID.

Dual EBNA1 promoter usage by Epstein-Barr virus in human B-cell lines expressing unique intermediate cellular phenotypes.

Mutational analysis of human papillomavirus E4 proteins: identification of structural features important in the formation of cytoplasmic E4/cytokeratin networks in epithelial cells.

The cytotoxicity of the autonomous parvovirus minute virus of mice nonstructural proteins in FR3T3 rat cells depends on oncogene expression.

Thermal inactivation of oral polio vaccine: contribution of RNA and protein inactivation.

Association of the reovirus S1 gene with serotype 3-induced biliary atresia in mice.

Alphavirus nsP3 functions to form replication complexes transcribing negative-strand RNA.

Molecular characterization of a newly recognized mouse parvovirus.

Identification and characterization of a 3C-like protease from rabbit hemorrhagic disease virus, a calicivirus.

Characterization of murine gammaherpesvirus 68 glycoprotein B (gB) homolog: similarity to Epstein-Barr virus gB (gp110).

Effects of human chromosome 12 on interactions between Tat and TAR of human immunodeficiency virus type 1.

Identification of signal sequences that control transcription of borna disease virus, a nonsegmented, negative-strand RNA virus.

Coronavirus M proteins accumulate in the Golgi complex beyond the site of virion budding.

Factors involved in entry of the human immunodeficiency virus type 1 into permissive cells: lack of evidence of a role for CD26.

Transduction of a human RNA sequence by poliovirus.

Functional complementation of the adenovirus E1B 19-kilodalton protein with Bcl-2 in the inhibition of apoptosis in infected cells.

The human cytomegalovirus origin of DNA replication (oriLyt) is the critical cis-acting sequence regulating replication-dependent late induction of the viral 1.2-kilobase RNA promoter.

Vaccine-induced neutralizing antibodies directed in part to the simian immunodeficiency virus (SIV) V2 domain were unable to protect rhesus monkeys from SIV experimental challenge.

Use of recombinant virus to assess human cytomegalovirus early and late promoters in the context of the viral genome.

Synergistic activation of simian immunodeficiency virus and human immunodeficiency virus type 1 transcription by retinoic acid and phorbol ester through an NF-kappa B-independent mechanism.

An assembly domain of the Rous sarcoma virus Gag protein required late in budding.

A cysteine protease encoded by the baculovirus Bombyx mori nuclear polyhedrosis virus.

Unusual heterogeneity of leader-mRNA fusion in a murine coronavirus: implications for the mechanism of RNA transcription and recombination.

Variable course of primary simian immunodeficiency virus infection in lymph nodes: relation to disease progression.

Efficient particle formation can occur if the matrix domain of human immunodeficiency virus type 1 Gag is substituted by a myristylation signal.

trans activation by the full-length E2 proteins of human papillomavirus type 16 and bovine papillomavirus type 1 in vitro and in vivo: cooperation with activation domains of cellular transcription factors.

Interference following mixed infection of reovirus isolates is linked to the M2 gene.

Human immunodeficiency virus type 1 evolution in vivo tracked by DNA heteroduplex mobility assays.

Dual tropism for macrophages and lymphocytes is a common feature of primary human immunodeficiency virus type 1 and 2 isolates.

A simian immunodeficiency virus envelope V3 cytotoxic T-lymphocyte epitope in rhesus monkeys and its restricting major histocompatibility complex class I molecule Mamu-A*02.

Functional importance of complex formation between the retinoblastoma tumor suppressor family and adenovirus E1A proteins as determined by mutational analysis of E1A conserved region 2.

Identification of three late expression factor genes within the 33.8- to 43.4-map-unit region of Autographa californica nuclear polyhedrosis virus.

Protective antibodies inhibit reovirus internalization and uncoating by intracellular proteases.

Mutational trends in V3 loop protein sequences observed in different genetic lineages of human immunodeficiency virus type 1.

Feline immunodeficiency virus decreases cell-cell communication and mitochondrial membrane potential.

Genetic identification of a novel hantavirus of the harvest mouse Reithrodontomys megalotis.

Borna disease virus: immunoelectron microscopic characterization of cell-free virus and further information about the genome.

Influence of infection route on the infectivity of baculovirus mutants lacking the apoptosis-inhibiting gene p35 and the adjacent gene p94.

Inhibition by interleukin-4 of constitutive beta interferon synthesis in mouse macrophages.

In murine AIDS, B cells are early targets of defective virus and are required for efficient infection and expression of defective virus in T cells and macrophages.

Characterization of a cleavage mutant of the measles virus fusion protein defective in syncytium formation.

Protein coding assignment of avian reovirus strain S1133.

The transactivator gene of human T-cell leukemia virus type I is more variable within and between healthy carriers than patients with tropical spastic paraparesis.

The activity of the protease of human immunodeficiency virus type 1 is initiated at the membrane of infected cells before the release of viral proteins and is required for release to occur with maximum efficiency.

Role of transcriptional repressors in transformation by bovine papillomavirus type 1.

Recombinant rabbit hemorrhagic disease virus capsid protein expressed in baculovirus self-assembles into viruslike particles and induces protection.

Human herpesvirus 6B origin: sequence diversity, requirement for two binding sites for origin-binding protein, and enhanced replication from origin multimers.

Tyrosine kinase activity may be necessary but is not sufficient for c-erbB1-mediated tissue-specific tumorigenicity.

Multiple adenovirus serotypes use alpha v integrins for infection.

Modulation of cellular macromolecular synthesis by coronavirus: implication for pathogenesis.

Transcription factor AP-2 regulates human immunodeficiency virus type 1 gene expression.

Characterization of a novel binding site for the human immunodeficiency virus type 1 envelope protein gp120 on human fetal astrocytes.

Susceptibility of Nonprimate Cell Lines to Hepatitis A Virus Infection

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Packaging of hepatitis delta virus RNA via the RNA-binding domain of hepatitis delta antigens: different roles for the small and large delta antigens.

Content Provider	PubMed Central
Author	Wang, H. W. Chen, P. J. Lee, C. Z. Wu, H. L. Chen, D. S.
Abstract	Hepatitis delta virus (HDV) is composed of four specific components. The first component is envelope protein which contains hepatitis B surface antigens. The second and third components are nucleocapsid proteins, referred to as small and large hepatitis delta antigens (HDAgs). The final component is a single-stranded circular RNA molecule known as the viral genome. In order to study the mechanism of HDV RNA packaging, a four-plasmid cotransfection system in which each viral component was provided by a separate plasmid was employed. Virus-like particles released from Huh-7 cells receiving such a cotransfection were found to contain HDV RNA along with three proteins. Therefore, the four-plasmid cotransfection system could lead to successful HDV RNA packaging in vitro. The system was then used to show that the large HDAg alone was able to achieve a low level of HDV RNA packaging. Analysis of a variety of large HDAg mutants revealed that the RNA-binding domain was essential for viral RNA packaging. By increasing the incorporation of small HDAg into virus-like particles, we found a three- to fourfold enhancement of HDV RNA packaging. This effect was probably through a direct binding of HDV RNA, independent from that of large HDAg, with the small HDAg. The subsequent RNA-protein complex was packaged into particles. The results provided insight into the roles and functional domains of small and large HDAgs in HDV RNA packaging.
Starting Page	6363
File Format	PDF
ISSN	10985514
e-ISSN	10985514
Journal	Journal of Virology
Issue Number	10
Volume Number	68
Language	English
Publisher Date	1994-10-01
Access Restriction	Open
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Virology Immunology Microbiology Insect Science

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