Please wait, while we are loading the content...
Please wait, while we are loading the content...
| Content Provider | PubMed Central |
|---|---|
| Author | Seraydarian, K. Mommaerts, W. F. H. M. |
| Abstract | Separation of particulate matter in rabbit muscle extracts by differential centrifugation leads, in first approximation, to the isolation of fraction I (15,000 to 41,000 g) and fraction II (41,000 to 150,000 g). The former consists mainly of sarcotubular material, actively transporting calcium ions, and displaying relaxation factor activity. The latter is heterogeneous, shows little calcium accumulation, and contains factors both inhibiting and activating myofibrillar ATPase. Fraction I is resolved by density gradient centrifugation into 2 main subfractions. The lighter one represents sarcotubular material in the best state of preservation, with biochemical activities stable for weeks in the cold. The heavier one may consist of the same material in a less well preserved form. Upon aging, it develops an activating activity toward myofibrillar ATPase, when the relaxing effect has declined. Fraction II is resolved by density gradient centrifugation into 3 or more fractions, with some variability. Relaxing activity in terms of inhibition of myofibrillar ATPase predominates among the lighter subfractions, increase of ATPase among the heavier. The intrinsic ATPase of fraction II is activated by calcium ions, but there is little or no bulk accumulation of calcium oxalate. Nevertheless, its limited calcium uptake seems to suffice to explain its relaxing activity. The particulate material contains mucopolysaccharide and lipid. Most of the lipid in fraction I is phospholipid; in fraction II this is less than half, if calculated as lecithin. The unfractionated material contains an adenylcyclase. There is no acetylcholine esterase. |
| Starting Page | 641 |
| File Format | |
| ISSN | 15408140 |
| e-ISSN | 15408140 |
| Journal | The Journal of Cell Biology |
| Issue Number | 2 |
| Volume Number | 26 |
| Language | English |
| Publisher | The Rockefeller University Press |
| Publisher Date | 1965-08-01 |
| Access Restriction | Open |
| Rights Holder | The Rockefeller University Press |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Medicine |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|