NDLI: Oral carriage of Candida albicans in murine AIDS.

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Identification of the gene family encoding the 160-kilodalton Trypanosoma cruzi complement regulatory protein.

Antibody- and cell-mediated immune responses of Actinobacillus pleuropneumoniae-infected and bacterin-vaccinated pigs.

Intravenous immunoglobulin inhibits staphylococcal toxin-induced human mononuclear phagocyte tumor necrosis factor alpha production.

Role of gamma interferon in the host immune and inflammatory responses to Pneumocystis carinii infection.

Nramp1 transfection transfers Ity/Lsh/Bcg-related pleiotropic effects on macrophage activation: influence on antigen processing and presentation.

Analysis of culture filtrate and cell wall-associated antigens of Mycobacterium paratuberculosis with monoclonal antibodies.

Salmonella typhi stimulation of human intestinal epithelial cells induces secretion of epithelial cell-derived interleukin-6.

Identification of extracellular phospholipase B, lysophospholipase, and acyltransferase produced by Cryptococcus neoformans.

Molecular characterization of a 6.6-kilodalton Borrelia burgdorferi outer membrane-associated lipoprotein (lp6.6) which appears to be downregulated during mammalian infection.

Role of the carboxyl-terminal region of Porphyromonas gingivalis fimbrillin in binding to salivary proteins.

Examination of diarrheagenicity of cytolethal distending toxin: suckling mouse response to the products of the cdtABC genes of Shigella dysenteriae.

Ferric iron reduction by Cryptococcus neoformans.

Pathogenesis of Acanthamoeba keratitis: carbohydrate-mediated host-parasite interactions.

Passive immunity to infection with Yersinia spp. mediated by anti-recombinant V antigen is dependent on polymorphism of V antigen.

Safety of live oral Salmonella typhi vaccine strains with deletions in htrA and aroC aroD and immune response in humans.

Evidence for a protective role of tumor necrosis factor in the acute phase of Trypanosoma cruzi infection in mice.

Role of coagulase in a murine model of hematogenous pulmonary infection induced by intravenous injection of Staphylococcus aureus enmeshed in agar beads.

Identification of neutralizing epitopes on Pseudomonas aeruginosa elastase and effects of cross-reactions on other thermolysin-like proteases.

Purification and characterization of Campylobacter rectus surface layer proteins.

Localization by site-directed mutagenesis of the site in human complement factor H that binds to Streptococcus pyogenes M protein.

Biochemical comparison of the Cu,Zn superoxide dismutases of Cryptococcus neoformans var. neoformans and Cryptococcus neoformans var. gattii.

Characterization, occurrence, and molecular cloning of a 39-kilodalton Brucella abortus cytoplasmic protein immunodominant in cattle.

A new putative fimbrial colonization factor, CS19, of human enterotoxigenic Escherichia coli.

Identification, characterization, and immunogenicity of the lactoferrin-binding protein from Helicobacter pylori.

A 140-kilodalton extracellular protein is essential for the accumulation of Staphylococcus epidermidis strains on surfaces.

A role for B cells in resistance to Cryptococcus neoformans in mice.

Escherichia coli K5 capsule expression enhances colonization of the large intestine in the gnotobiotic rat.

Identification of D motif epitopes in Staphylococcus aureus fibronectin-binding protein for the production of antibody inhibitors of fibronectin binding.

Intranasal priming with recombinant Bordetella pertussis for the induction of a systemic immune response against a heterologous antigen.

Role of aspartic proteases in disseminated Candida albicans infection in mice.

Cryptococcal polysaccharides bind to CD18 on human neutrophils.

Th1 and Th2 cytokines in mice with invasive aspergillosis.

Topology of Legionella pneumophila DotA: an inner membrane protein required for replication in macrophages.

Pseudomonas aeruginosa-mediated cytotoxicity and invasion correlate with distinct genotypes at the loci encoding exoenzyme S.

Simultaneous prevention of glutamine synthesis and high-affinity transport attenuates Salmonella typhimurium virulence.

Stabilized expression of mRNA is associated with mycobacterial resistance controlled by Nramp1.

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The central variable V2 region of the CS31A major subunit is involved in the receptor-binding domain.

Induction of biologically active interleukin-8 from lung epithelial cells by Burkholderia (Pseudomonas) cepacia products.

Adjuvant modulation of immune responses to tuberculosis subunit vaccines.

Critical roles of neutrophils in host defense against experimental systemic infections of mice by Listeria monocytogenes, Salmonella typhimurium, and Yersinia enterocolitica.

Protegrin structure and activity against Neisseria gonorrhoeae.

Oral immunization with PspA elicits protective humoral immunity against Streptococcus pneumoniae infection.

Selection of Opa+ Neisseria gonorrhoeae by limited availability of normal human serum.

Identification of tandem genes involved in lipooligosaccharide expression by Haemophilus ducreyi.

Oral carriage of Candida albicans in murine AIDS.

Cloning and sequence analysis of the gbpC gene encoding a novel glucan-binding protein of Streptococcus mutans.

Induction of cytotoxic T-cell responses against culture filtrate antigens in Mycobacterium bovis bacillus Calmette-Guérin-infected mice.

gamma-Glutamyltransferase from the outer cell envelope of Treponema denticola ATCC 35405.

Effects of Mycobacterium tuberculosis on the bioelectric properties of the alveolar epithelium.

Cytokine and adhesion molecule expression in human monocytes and endothelial cells stimulated with bacterial heat shock proteins.

Role of SefA subunit protein of SEF14 fimbriae in the pathogenesis of Salmonella enterica serovar Enteritidis.

Reactivity patterns and epitope specificities of anti-Cryptococcus neoformans monoclonal antibodies by enzyme-linked immunosorbent assay and dot enzyme assay.

Invasion of Vero cells and induction of apoptosis in macrophages by pathogenic Leptospira interrogans are correlated with virulence.

In situ characterization of inflammatory responses in the rectal mucosae of patients with shigellosis.

Inhibition of Helicobacter pylori binding to gastrointestinal epithelial cells by sialic acid-containing oligosaccharides.

Characterization of the Chlamydia trachomatis vacuole and its interaction with the host endocytic pathway in HeLa cells.

Mycobacterium marinum causes both long-term subclinical infection and acute disease in the leopard frog (Rana pipiens).

Secretion of Shigella flexneri Ipa invasins on contact with epithelial cells and subsequent entry of the bacterium into cells are growth stage dependent.

Proteophosphoglycan secreted by Leishmania mexicana amastigotes causes vacuole formation in macrophages.

IpaB, a Shigella flexneri invasin, colocalizes with interleukin-1 beta-converting enzyme in the cytoplasm of macrophages.

Identification of a frameshift mutation resulting in premature termination and loss of cell wall anchoring of the PAc antigen of Streptococcus mutans GS-5.

Protection against infection in mice vaccinated with a Brucella abortus mutant.

Production of monoclonal antibodies to the non-membrane-damaging cytotoxin (NMDCY) purified from Vibrio cholerae O26 and distribution of NMDCY among strains of Vibrio cholerae and other enteric bacteria determined by monoclonal-polyclonal sandwich enzyme-linked immunosorbent assay.

Similarities and disparities between core-specific and O-side-chain-specific antilipopolysaccharide monoclonal antibodies in models of endotoxemia and bacteremia in mice.

Porphyromonas gingivalis fimbria-stimulated bone resorption is inhibited through binding of the fimbriae to fibronectin.

Expression of aerobactin genes by Shigella flexneri during extracellular and intracellular growth.

Characterization of the diversity and the transferrin-binding domain of gonococcal transferrin-binding protein 2.

Avirulence of Candida albicans FAS2 mutants in a mouse model of systemic candidiasis.

Reduced virulence of Candida albicans MKC1 mutants: a role for mitogen-activated protein kinase in pathogenesis.

Development of a murine model of chronic Salmonella infection.

Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion.

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Oral carriage of Candida albicans in murine AIDS.

Content Provider	PubMed Central
Author	Deslauriers, N. Côté, L. Montplaisir, S. De, Repentigny L.
Abstract	Oral candidiasis is a common fungal infection in patients infected with the human immunodeficiency virus (HIV). Although rare at the time of primary HIV infection, it is frequently found throughout the asymptomatic phase and is predictive of progressive immunodeficiency. However, the precise immune defect which results in outgrowth of commensal Candida albicans in HIV infection has not been identified. Mice infected with the Du5H(G6T2) mixture of mouse leukemia viruses develop a syndrome, designated murine AIDS (MAIDS), that has many of the immune abnormalities found in HIV infection. Retrovirus-infected C57BL/6 mice were examined for their ability to resist the development of oral candidiasis from the carrier state established after a self-limiting acute infection and to clear a subsequent secondary inoculum of oral C. albicans. Most of the mice orally colonized with C. albicans and then inoculated with the retrovirus mixture maintained a low-level oral carriage of C. albicans, while 30% of coinfected mice developed recurring 2- to 3-week episodes of acute Candida proliferation, separated by transient recoveries to the carrier state. The frequencies of CD4+ and CD8+ lymphocytes were, respectively, unchanged and significantly decreased (P < 0.05) in both cervical lymph nodes and spleens of coinfected mice compared to the corresponding frequencies in C. albicans-carrying, virus-free, age-matched control animals. Secretion of gamma interferon by concanavalin A (ConA)-stimulated spleen cells from Candida-carrying, retrovirus-infected mice was significantly decreased (P < 0.05) compared to that of C. albicans-carrying, retrovirus-free mice, in accordance with known abnormalities associated with MAIDS. However, production of this cytokine by ConA-stimulated or unstimulated cervical lymph node cells from coinfected mice was enhanced compared to that of virus-free animals colonized with C. albicans. Acquired resistance to reinfection with C. albicans was maintained in retrovirus-infected mice and was associated with a mucosal recruitment of CD8+ cells not observed in control mice. These results suggest that alterations in mucosal immunity which occur in MAIDS differ substantially from defects observed at other sites and that surrogate epithelial defense mechanisms may function locally to limit Candida proliferation.
Starting Page	661
File Format	PDF
ISSN	10985522
e-ISSN	10985522
Journal	Infection and Immunity
Issue Number	2
Volume Number	65
Language	English
Publisher Date	1997-02-01
Access Restriction	Open
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Infectious Diseases Parasitology Immunology Microbiology

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