Please wait, while we are loading the content...
Please wait, while we are loading the content...
| Content Provider | PubMed Central |
|---|---|
| Author | Johnson, D. A. |
| Abstract | 1. The response of parasympathetic neurones to the removal of preganglionic innervation was studied in the ciliary ganglia of adult rabbits. After section of the preganglionic oculomotor nerve, individual ciliary neurones were characterized electrophysiologically by intracellular recording, and morphologically by intracellular injection of horseradish peroxidase. 2. Within the first 24-48 h after nerve section, only two of fifty-nine neurones responded to antidromic stimulation of the postganglionic ciliary nerve with synaptic potentials. This result indicates that synaptic connections between principal neurones are rare in normal ganglia. 3. One week after denervation, however, excitatory postsynaptic potentials were recorded in thirty-nine out of fifty-three cells examined. Thus there is a rapid and extensive formation of intraganglionic connections after denervation. Morphological analysis of these ganglion cells showed numerous fine processes arising from the cell bodies and dendrites; such neurites were not present among control neurones. Many of these newly formed processes appeared to form synapses on neighbouring cells. 4. A similar proportion of neurones (about two-thirds of the cells) showed antidromically evoked excitatory postsynaptic potentials 2 weeks after denervation. Dendrites were still longer and more complex than controls at this time. After several months the morphology and prevalence of intraganglionic connections returned to normal as the ganglion became reinnervated. 5. Thus, denervation of rabbit ciliary ganglion cells induces the rapid formation of large numbers of functional synaptic connections among ganglion cells. It is postulated that local regulatory factors govern connections between parasympathetic ganglion cells. After denervation, these trophic signals are no longer modulated by presynaptic axons and they exert a stimulus for sprouting and synapse formation among this population of cholinergic neurones. |
| Ending Page | 62 |
| Starting Page | 51 |
| File Format | |
| ISSN | 14697793 |
| e-ISSN | 14697793 |
| Journal | The Journal of Physiology |
| Volume Number | 397 |
| Language | English |
| Publisher Date | 1988-03-01 |
| Access Restriction | Open |
| Subject Keyword | Research in Higher Education |
| Content Type | Text |
| Resource Type | Article |
| Subject | Physiology Sports Science |
National Digital Library of India (NDLI) is a virtual repository of learning resources which is not just a repository with search/browse facilities but provides a host of services for the learner community. It is sponsored and mentored by Ministry of Education, Government of India, through its National Mission on Education through Information and Communication Technology (NMEICT). Filtered and federated searching is employed to facilitate focused searching so that learners can find the right resource with least effort and in minimum time. NDLI provides user group-specific services such as Examination Preparatory for School and College students and job aspirants. Services for Researchers and general learners are also provided. NDLI is designed to hold content of any language and provides interface support for 10 most widely used Indian languages. It is built to provide support for all academic levels including researchers and life-long learners, all disciplines, all popular forms of access devices and differently-abled learners. It is designed to enable people to learn and prepare from best practices from all over the world and to facilitate researchers to perform inter-linked exploration from multiple sources. It is developed, operated and maintained from Indian Institute of Technology Kharagpur.
Learn more about this project from here.
NDLI is a conglomeration of freely available or institutionally contributed or donated or publisher managed contents. Almost all these contents are hosted and accessed from respective sources. The responsibility for authenticity, relevance, completeness, accuracy, reliability and suitability of these contents rests with the respective organization and NDLI has no responsibility or liability for these. Every effort is made to keep the NDLI portal up and running smoothly unless there are some unavoidable technical issues.
Ministry of Education, through its National Mission on Education through Information and Communication Technology (NMEICT), has sponsored and funded the National Digital Library of India (NDLI) project.
| Sl. | Authority | Responsibilities | Communication Details |
|---|---|---|---|
| 1 | Ministry of Education (GoI), Department of Higher Education |
Sanctioning Authority | https://www.education.gov.in/ict-initiatives |
| 2 | Indian Institute of Technology Kharagpur | Host Institute of the Project: The host institute of the project is responsible for providing infrastructure support and hosting the project | https://www.iitkgp.ac.in |
| 3 | National Digital Library of India Office, Indian Institute of Technology Kharagpur | The administrative and infrastructural headquarters of the project | Dr. B. Sutradhar bsutra@ndl.gov.in |
| 4 | Project PI / Joint PI | Principal Investigator and Joint Principal Investigators of the project |
Dr. B. Sutradhar bsutra@ndl.gov.in Prof. Saswat Chakrabarti will be added soon |
| 5 | Website/Portal (Helpdesk) | Queries regarding NDLI and its services | support@ndl.gov.in |
| 6 | Contents and Copyright Issues | Queries related to content curation and copyright issues | content@ndl.gov.in |
| 7 | National Digital Library of India Club (NDLI Club) | Queries related to NDLI Club formation, support, user awareness program, seminar/symposium, collaboration, social media, promotion, and outreach | clubsupport@ndl.gov.in |
| 8 | Digital Preservation Centre (DPC) | Assistance with digitizing and archiving copyright-free printed books | dpc@ndl.gov.in |
| 9 | IDR Setup or Support | Queries related to establishment and support of Institutional Digital Repository (IDR) and IDR workshops | idr@ndl.gov.in |
|
Loading...
|