NDLI: Phencyclidine

Content Provider	PubMed Central
Author	Burns, R. Stanley Lerner, Steven E. Corrado, Robbie James, Stuart H. Schnoll, Sidney H.
Abstract	Phencyclidine is now one of the most frequently used main ingredients of “street drug” preparations. Its effects are highly dose dependent and three varieties of acute intoxication have been seen clinically associated with different dosages and routes of administration. Most persons using phencyclidine smoke it sprinkled on parsley in low doses. The presence of horizontal and vertical nystagmus associated with hypertension in a patient who is agitated or comatose are diagnostic of a phencyclidine intoxicated state. Sensory isolation and intravenous administration of diazepam in the event of seizure activity have proved effective in the treatment of acute intoxicated states. Phencyclidine has pronounced behavioral toxicity and several deaths due to this agent have now been documented. It is unknown whether seizure activity or respiratory depression is the primary cause of death in pharmacological overdoses.
Starting Page	345
File Format	PDF
ISSN	00930415
Journal	Western Journal of Medicine
Issue Number	5
Volume Number	123
Language	English
Publisher Date	1975-11-01
Access Restriction	Open
Subject Keyword	Research in Higher Education
Content Type	Text
Resource Type	Article
Subject	Medicine

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Phencyclidine—