NDLI: Well-being and Cognitive Resilience to Dementia-related Neuropathology

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Well-being and Cognitive Resilience to Dementia-related Neuropathology

Content Provider	PsyArXiv
Author	Willroth, Emily C James, Bryan Graham, Eileen Kranz Kapasi, Alifiya Bennett, David Mroczek, Dan
Description	Not all older adults with dementia-related neuropathology in their brains experience cognitive decline or impairment. Instead, some people maintain relatively normal cognitive functioning despite neuropathologic burden, a phenomenon called cognitive resilience. Using a longitudinal, epidemiological, clinical-pathologic cohort study (N=348), the present research investigated associations between well-being and cognitive resilience. Consistent with pre-registered hypotheses, higher eudaimonic well-being (i.e., Ryff Psychological Well-being Scale) and higher hedonic well-being (i.e., Satisfaction with Life Scale) were associated with better-than-expected cognitive functioning relative to one’s neuropathological burden (i.e., beta-amyloid, neurofibrillary tangles, Lewy bodies, vascular pathologies, hippocampal sclerosis, and TDP-43). The association of eudaimonic well-being in particular was present above and beyond known cognitive resilience factors (i.e., socioeconomic status, education, cognitive activity, low neuroticism, low depression) and dementia risk factors (i.e., ApoE genotype, medical comorbidities). This research highlights the importance of considering eudaimonic well-being in efforts to prevent dementia.
DOI	10.31234/osf.io/sbh85
Language	English
Publisher Date	2022-07-12
Access Restriction	Open
Rights License	CC-By Attribution 4.0 International
Subject Keyword	Social and Behavioral Sciences;Psychology, other Alzheimer's Disease Cognitive Resilience Dementia Eudaimonic Hedonic Life Satisfaction Psychological Well-being Subjective Well-being Well-being
Content Type	Text
Resource Type	Preprint
Subject	Social Sciences Psychology

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