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Chicken or egg—Weismann revisited
| Content Provider | Paperity |
|---|---|
| Author | Nick, Peter |
| Abstract | Multicellularity allows for division of labour. This requires that individual cells adopt different developmental fates. This developmental dichotomy could arise from interactions between the cells, but it could as well be produced by a formative cell division guided by a gradient of developmental determinants within the progenitor cell such that these determinants are differentially partitioned to the daughter cells. It was August Weismann, who, in the attempt to explain inheritance, proposed that the first gonidial division should define the separation of the differentiating, but mortal soma from the non-differentiating, but immortal germ line as a primordial event of multicellular development (Weismann 1894). Although he could not foresee the concept of differential gene expression at this time, the soma-germ line concept has been fruitful to describe early development of the metazoa. Following the Weismann concept, the ultimate cause for cell differentiation and morphogenesis of th ... |
| Starting Page | 729 |
| Ending Page | 730 |
| File Format | HTM / HTML |
| ISSN | 0033183X |
| DOI | 10.1007/s00709-014-0656-6 |
| Issue Number | 4 |
| Journal | Protoplasma |
| Volume Number | 251 |
| e-ISSN | 16156102 |
| Language | English |
| Publisher | Springer Vienna |
| Publisher Date | 2014-06-17 |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Plant Science Medicine |