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Incidencia de episodios febriles en pacientes con mieloma múltiple sometidos a trasplante autólogo de progenitores hematopoyéticos de sangre periférica (TASPE)
| Content Provider | Paperity |
|---|---|
| Author | Lozano, J. J. Gimeno Fernández-mosteirín, N. Salvador-osuna, C. Alberdi, M. Blasco Lamata, M. L. Marco Raichs, M. Giralt Félix, D. Rubio |
| Abstract | Background: Autologous peripheral blood stem cell transplantation (PBSCT) is a procedure frequently used as therapy for hematological malignancies, in wich infectious complications are a major cause of morbimortality. The duration and intensity of neutropenia, indwelling central venous catheters, and mucosa chemotherapy-induced damage, contribute to increase infection rates. We have retrospectively review the incidence of febrile episodes and microbiological documented infections (MDI) in patients with multiple myeloma (MM) undergoing PBSCT. Patients and methods: We have retrospectively analized 56 PBSCT in patients diagnosed of MM between 1995 and 2002 in our hospital. Results: 34 patients showed fever: 19 fever of unknown origin; 5 clinically documented infections and 10 patients MDI. We isolated 5 pathogens gram negative and 4 gram positive. We observed 2 infections associated to indwelling central venous catheters and 1 MDI due to simplex Herpes Virus. Two patiens died due to infectious complications. Conclusions: The incidence of febrile episodes in our patients is similar to those previously reported as well, duration of neutropenia associated to PBSCT. We have observed a slightly higher incidence of gram negative pathogens. |
| Starting Page | 213 |
| Ending Page | 216 |
| File Format | HTM / HTML |
| ISSN | 02127199 |
| Issue Number | 5 |
| Journal | Anales de Medicina Interna |
| Volume Number | 22 |
| Language | English Spanish |
| Publisher Date | 2005-01-05 |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
| Subject | Internal Medicine |
