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Distribución de patrones PRA en aislamientos clínicos del complejo Mycobacterium avium procedentes de España y Suramérica
| Content Provider | Paperity |
|---|---|
| Author | Oliveira, Rosangela Siqueira De Murcia, Martha Isabel Leao, Sylvia Cardoso Menendez, Maria Carmen Hadad, David Jamil Ritacco, Viviana Reniero, Ana García, María Jesús Telles, María Alice Da Silva Barrera, Lucía Palenque, Elia |
| Abstract | Distribution of PRA patterns of clinical isolates of the Mycobacterium avium complex from Spain and South America Mycobacterium avium complex (MAC) infections are the most frequent systemic infections associated with advanced AIDS. DNA probes for accurate identification of mycobacteria are available but are very expensive in many Latin American settings. Consequently, most Latin American diagnostic laboratories employ inaccurate and outdated tests for mycobacteria identification. Therefore, PCR restriction analysis (PRA) of the hsp65 gene was evaluated for the identification of 163 MAC human isolates originated from Spain and South America. The predominant PRA type in each country was: M. avium type I in Argentina (23/42, 55%) and Brazil (48/72, 67%), M. avium type II in Spain (18/26, 69%) and M. avium type III in Colombia (10/ 23, 43%). The Colombia frequency is noteworthy, since the PRA type III was quite infrequent in the other three countries. Furthermore, its presence has not been reported outside the Americas. The advantages and disadvantages of PRA in diagnostic mycobacteriology are discussed |
| Starting Page | 60 |
| Ending Page | 64 |
| File Format | HTM / HTML |
| ISSN | 01204157 |
| Journal | Biomédica |
| Volume Number | 24 |
| Language | English Spanish |
| Publisher Date | 2004-01-06 |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
| Subject | Medicine Biochemistry, Genetics and Molecular Biology |
