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Successful treatment of refractory acquired pure red cell aplasia (PRCA) by allogeneic bone marrow transplantation
| Content Provider | Paperity |
|---|---|
| Author | Nissen, C. Wodnar-filipowicz, A. Passweg, Jr Gratwohl, A. Tichelli, A. Müller, Bu |
| Abstract | This case describes a 16-year-old woman treated successfully by a bone marrow transplant from her HLA-identical brother for refractory acquired pure red cell aplasia. Conditioning was as for severe aplastic anaemia with cyclophosphamide 4 × 50 mg/kg and antithymocyte globulin. Complete donor type engraftment at 3 months reversed to full autologous reconstitution at 2 years with normal haemopoiesis. The potential implications on pathogenesis of the disease as well as on treatment of autoimmune disorders by stem cell transplantation are discussed. |
| Starting Page | 1205 |
| Ending Page | 1207 |
| File Format | HTM / HTML |
| DOI | 10.1038/sj.bmt.1701785 |
| Journal | Bone Marrow Transplantation |
| Volume Number | 23 |
| e-ISSN | 14765365 |
| Language | English |
| Publisher | Nature Publishing Group |
| Publisher Date | 1999-05-20 |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
