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Nitroxyl (HNO): A Reduced Form of Nitric Oxide with Distinct Chemical, Pharmacological, and Therapeutic Properties
| Content Provider | Paperity |
|---|---|
| Author | Aly, Omar M. Shoman, Mai E. |
| Abstract | Nitroxyl (HNO), the one-electron reduced form of nitric oxide (NO), shows a distinct chemical and biological profile from that of NO. HNO is currently being viewed as a vasodilator and positive inotropic agent that can be used as a potential treatment for heart failure. The ability of HNO to react with thiols and thiol containing proteins is largely used to explain the possible biological actions of HNO. Herein, we summarize different aspects related to HNO including HNO donors, chemistry, biology, and methods used for its detection. |
| File Format | HTM / HTML |
| ISSN | 19420900 |
| DOI | 10.1155/2016/4867124 |
| Journal | Oxidative Medicine and Cellular Longevity |
| Volume Number | 2016 |
| e-ISSN | 19420994 |
| Language | English |
| Publisher | Hindawi Limited |
| Publisher Date | 2015-12-07 |
| Access Restriction | Open |
| Content Type | Text |
| Resource Type | Article |
| Subject | Cell Biology Aging Medicine Biochemistry |