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Trachoma prevalence remains below threshold in five districts after stopping mass drug administration: results of five surveillance surveys within a hyperendemic setting in Amhara, Ethiopia
| Content Provider | Oxford Academic |
|---|---|
| Author | Nash, Scott D Stewart, Aisha E P Astale, Tigist Sata, Eshetu Zerihun, Mulat Gessese, Demelash Melak, Berhanu Ayenew, Gedefaw Ayele, Zebene Bayissasse, Belay Chanyalew, Melsew Tadesse, Zerihun Callahan, E Kelly |
| Copyright Year | 2018 |
| Abstract | BackgroundThe World Health Organization (WHO) recommends conducting trachoma surveillance surveys in districts where the elimination targets have been met and following a minimum 2-year period after cessation of mass drug administration (MDA) in order to determine the sustainability of low trachoma levels.MethodsIn 2015, population-based surveillance surveys were conducted in five districts of Amhara, Ethiopia. All five districts had a prior trachomatous inflammation–follicular (TF) prevalence among children 1–9 y of age of <5% determined by an impact survey and had not received MDA for ≥2 y. Surveys included examinations for trachoma clinical signs and conjunctival swabbing to determine Chlamydia trachomatis infection prevalence.ResultsApproximately 1000 children 1–9 y of age were examined for TF and 200 children 1–5 y of age were swabbed per district. All five surveillance districts had a TF prevalence of <5% and infection was only detected in one district. The prevalence of trachomatous trichiasis in adults ≥15 y of age was ≥1% in all districts.ConclusionsIn a trachoma hyperendemic region, a TF prevalence <5% was successfully maintained in five districts for ≥2 years after stopping MDA. MDA is still not warranted for these districts, however, the S, F and E components of the SAFE strategy should continue. |
| Related Links | https://academic.oup.com/trstmh/article-pdf/112/12/538/26756350/try096.pdf |
| Ending Page | 545 |
| Starting Page | 538 |
| File Format | |
| ISSN | 00359203 |
| e-ISSN | 18783503 |
| DOI | 10.1093/trstmh/try096 |
| Journal | Transactions of The Royal Society of Tropical Medicine and Hygiene |
| Issue Number | 12 |
| Volume Number | 112 |
| Language | English |
| Publisher | Oxford Academic |
| Publisher Date | 2018-12-01 |
| Access Restriction | Open |
| Subject Keyword | Clinical Medicine Infectious Diseases Medicine and Health Public Health and Epidemiology Ethiopia Trachoma Surveillance, Medical Mass Drug Administration Child Infections Chlamydia Trachomatis Neglected Tropical Diseases Surveillance Surveys |
| Content Type | Text |
| Resource Type | Article |
| Subject | Infectious Diseases Public Health, Environmental and Occupational Health Parasitology |
