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DIURETIC ACTIVITY OF LEAVES OF BALANITES ROXBURGHII LINN.
| Content Provider | Open Access Library (OALib) |
|---|---|
| Author | Nitin S. Wani |
| Abstract | Balanites roxburghii is a spiny, evergreen tree. It is common in open sandy plains of the Indian peninsula, western Rajastan, west Bengal, Maharashtra and drier parts of India. The dried leaves of Balanites Roxburghii Linn. were subjected to successive extraction using the solvents ethanol and methanol. The prepared extracts were then subjected to preliminary phytochemical screening. It was found that the plant possesses alkaloids, glycosides, saponins, flavones and phenolic compounds. The diuretic effect was examined by treating different groups of wistar albino rats with (150 and 300mg/kg) oral doses of ethanol and methanol extracts. The volumes of urine, urinary concentration of sodium and potassium ions were the parameters of the study. Frusemide was used as standard. The results indicate that ethanol and methanol extract at 300 mg/kg body weight shows a significant (p<0.05) increase in the urine volume and electrolyte excretion (p<0.001) when compared to control. Methanol extract show significant diuretic activity. From the present study it may be concluded that the constituents present in methanol extracts may be responsible for diuretic activity |
| ISSN | 09749446 |
| Journal | International Journal of Pharmaceutical Research and Development |
| Publisher | rtechnology |
| Publisher Date | 2010-01-01 |
| Access Restriction | Open |
| Subject Keyword | Balanites Roxburghii Diuretic Ethanol and methanol extract |
| Content Type | Text |
| Resource Type | Article |
