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Investigation of Red Blood Cells by Atomic Force Microscopy
| Content Provider | MDPI |
|---|---|
| Author | Sergunova, Viktoria Leesment, Stanislav Kozlov, Aleksandr Inozemtsev, Vladimir Platitsina, Polina Lyapunova, Snezhanna Onufrievich, Alexander Polyakov, Vyacheslav Sherstyukova, Ekaterina |
| Copyright Year | 2022 |
| Description | Currently, much research is devoted to the study of biological objects using atomic force microscopy (AFM). This method’s resolution is superior to the other non-scanning techniques. Our study aims to further emphasize some of the advantages of using AFM as a clinical screening tool. The study focused on red blood cells exposed to various physical and chemical factors, namely hemin, zinc ions, and long-term storage. AFM was used to investigate the morphological, nanostructural, cytoskeletal, and mechanical properties of red blood cells (RBCs). Based on experimental data, a set of important biomarkers determining the status of blood cells have been identified. |
| Starting Page | 2055 |
| e-ISSN | 14248220 |
| DOI | 10.3390/s22052055 |
| Journal | Sensors |
| Issue Number | 5 |
| Volume Number | 22 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-03-07 |
| Access Restriction | Open |
| Subject Keyword | Sensors Imaging Atomic Force Microscopy Red Blood Cells Morphology Nanostructure Cytoskeleton Membrane Stiffness |
| Content Type | Text |
| Resource Type | Article |
