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Comparative Pathology of Zoonotic Orthopoxviruses
| Content Provider | MDPI |
|---|---|
| Author | Neill, Amy L. Mac |
| Copyright Year | 2022 |
| Description | This review provides a brief history of the impacts that a human-specific Orthopoxvirus (OPXV), Variola virus, had on mankind, recalls how critical vaccination was for the eradication of this disease, and discusses the consequences of discontinuing vaccination against OPXV. One of these consequences is the emergence of zoonotic OPXV diseases, including Monkeypox virus (MPXV). The focus of this manuscript is to compare pathology associated with zoonotic OPXV infection in veterinary species and in humans. Efficient recognition of poxvirus lesions and other, more subtle signs of disease in multiple species is critical to prevent further spread of poxvirus infections. Additionally included are a synopsis of the pathology observed in animal models of MPXV infection, the recent spread of MPXV among humans, and a discussion of the potential for this virus to persist in Europe and the Americas. |
| Starting Page | 892 |
| e-ISSN | 20760817 |
| DOI | 10.3390/pathogens11080892 |
| Journal | Pathogens |
| Issue Number | 8 |
| Volume Number | 11 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-08-09 |
| Access Restriction | Open |
| Subject Keyword | Pathogens Virology Akhmeta Virus Alaskapox Virus Buffalopox Virus Camelpox Virus Cowpox Virus Horsepox Virus Monkeypox Virus Vaccinia Virus |
| Content Type | Text |
| Resource Type | Article |
