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Epidemiology and Molecular Analyses of Influenza B Viruses in Senegal from 2010 to 2019
| Content Provider | MDPI |
|---|---|
| Author | Cheikh, Talibouya Touré Fall, Amary Andriamandimby, Soa Fy Jallow, Mamadou Malado Goudiaby, Deborah Kiori, Davy Sy, Sara Diaw, Yague Ndiaye, Koba Ndiende Mbaye, Fatimata Niang, Mbayang Ndiaye Heraud, Jean Michel Dia, Ndongo |
| Copyright Year | 2022 |
| Description | Influenza virus types A and B are responsible for acute viral infections that affect annually 1 billion people, with 290,000 to 650,000 deaths worldwide. In this study, we investigated the circulation of influenza B viruses over a 10-year period (2010–2019). Specimens from patients suspected of influenza infection were collected. Influenza detection was performed following RNA extraction and real-time RT-PCR. Genes coding for hemagglutinin (HA) and neuraminidase (NA) of influenza B viruses were partially sequenced, and phylogenetic analyses were carried out subsequently. During the study period, we received and tested a total of 15,156 specimens. Influenza B virus was detected in 1322 (8.7%) specimens. The mean age of influenza B positive patients was 10.9 years. When compared to reference viruses, HA genes from Senegalese circulating viruses showed deletions in the HA1 region. Phylogenetic analysis highlighted the co-circulation of B/Victoria and B/Yamagata lineage viruses with reassortant viruses. We also noted a clear seasonal pattern of circulation of influenza B viruses in Senegal. |
| Starting Page | 1063 |
| e-ISSN | 19994915 |
| DOI | 10.3390/v14051063 |
| Journal | Viruses |
| Issue Number | 5 |
| Volume Number | 14 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-05-16 |
| Access Restriction | Open |
| Subject Keyword | Viruses Infectious Diseases Influenza B Surveillance Epidemiology Phylogenetic Analyses Reassorting Viruses Senegal Africa |
| Content Type | Text |
| Resource Type | Article |
