NDLI: Regenerative Stem Cell Therapy for Neurodegenerative Diseases: An Overview

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Regenerative Stem Cell Therapy for Neurodegenerative Diseases: An Overview

Content Provider	MDPI
Author	Sivandzade, Farzane Cucullo, Luca
Copyright Year	2021
Description	Neurodegenerative diseases resulting from the progressive loss of structure and/or function of neurons contribute to different paralysis degrees and loss of cognition and sensation. The lack of successful curative therapies for neurodegenerative disorders leads to a considerable burden on society and a high economic impact. Over the past 20 years, regenerative cell therapy, also known as stem cell therapy, has provided an excellent opportunity to investigate potentially powerful innovative strategies for treating neurodegenerative diseases. This is due to stem cells’ capability to repair injured neuronal tissue by replacing the damaged or lost cells with differentiated cells, providing a conducive environment that is in favor of regeneration, or protecting the existing healthy neurons and glial cells from further damage. Thus, in this review, the various types of stem cells, the current knowledge of stem-cell-based therapies in neurodegenerative diseases, and the recent advances in this field are summarized. Indeed, a better understanding and further studies of stem cell technologies cause progress into realistic and efficacious treatments of neurodegenerative disorders.
Starting Page	2153
e-ISSN	14220067
DOI	10.3390/ijms22042153
Journal	International Journal of Molecular Sciences
Issue Number	4
Volume Number	22
Language	English
Publisher	MDPI
Publisher Date	2021-02-22
Access Restriction	Open
Subject Keyword	International Journal of Molecular Sciences Cell Tissue Engineering Stem Cells Therapy Regenerative Neurodegenerative Diseases Parkinson's Disease Huntington's Disease Alzheimer's Disease Amyotrophic Lateral Sclerosis
Content Type	Text
Resource Type	Article

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