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Association between Vitamin D and Candida-Associated Denture Stomatitis
| Content Provider | MDPI |
|---|---|
| Author | Miranda, Muhvić-Urek Ema, Saltović Daniela, Kovačević Pavičić Braut, Alen |
| Copyright Year | 2020 |
| Description | Candida-associated denture stomatitis (CADS) is a fungal infection affecting 60–65% of denture wearers. Its etiology is complex and multifactorial and often associated with host immunodeficiency. Evidence exists that vitamin D has potential immunomodulatory and anti-inflammatory effects. The aim of this case–control study was to assess the association between vitamin D levels and CADS. The study included 32 complete denture wearers with CADS and 32 sex- and age-matched complete denture wearers without CADS. The patients were clinically examined, and the severity of denture stomatitis was assessed according to Newton’s classification scale. The serum vitamin D level was determined via the use of an electrochemiluminescence assay. The vitamin D level in the CADS group and control group was 54.68 ± 17.07 and 56.82 ± 17.75 nmol/L, respectively. There was no significant difference between the groups (p = 0.622). Univariate logistic regression analysis showed that the presence of CADS was not associated with hypovitaminosis D (odds ratio (OR) = 1.44; 95% confidence interval (CI) = 0.37–5.54). It can be concluded that vitamin D is not associated with CADS and does not play a significant role in host susceptibility to CADS. This finding suggests that vitamin D screening is not indicated routinely in patients with Candida-associated denture stomatitis. |
| Starting Page | 121 |
| e-ISSN | 23046767 |
| DOI | 10.3390/dj8040121 |
| Journal | Dentistry Journal |
| Issue Number | 4 |
| Volume Number | 8 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2020-10-21 |
| Access Restriction | Open |
| Subject Keyword | Dentistry Journal Dentistry and Oral Surgery 25-hydroxyvitamin D Candidiasis Oral Stomatitis Denture Vitamin D |
| Content Type | Text |
| Resource Type | Article |
