NDLI: Potential Beneficial Effects of Chenopodium quinoa and Salvia hispanica L. in Glucose Homeostasis in Hyperglycemic Mice Model

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Potential Beneficial Effects of Chenopodium quinoa and Salvia hispanica L. in Glucose Homeostasis in Hyperglycemic Mice Model

Content Provider	MDPI
Author	Selma-Gracia, Raquel Haros, Claudia Monika Laparra, José Moisés
Copyright Year	2020
Description	Impaired glucose homeostasis is associated with an increased risk of developing metabolic alterations. In this study, a model in which mice treated with streptozotocin were fed a high-fat diet was used to mimic early stages of the onset of metabolic disorders, and different bread formulations were administrated to evaluate the effect of replacing wheat flour with Chenopodium quinoa (Q) (25%) and Salvia hispanica L. (Sh) (20%). Plasmatic glucose and insulin concentrations were quantified and the homeostasis model assessment (HOMAir) was calculated. Q and Sh showed a lower tendency to hyperglycemia compared to wheat bread (WB). Besides, these low glucose levels were accompanied by three-fold lower values of HOMAir respect to WB, suggesting an improved insulin sensitivity. Thus, inclusion of C. quinoa and S. hispanica into bread formulations could improve the control of glucose homeostasis, which could help to prevent/ameliorate metabolic glucose alterations.
Starting Page	2
e-ISSN	25043900
DOI	10.3390/proceedings2020053002
Journal	Proceedings
Issue Number	1
Volume Number	53
Language	English
Publisher	MDPI
Publisher Date	2020-08-03
Access Restriction	Open
Subject Keyword	Proceedings Food Science and Technology Chenopodium Quinoa Salvia Hispanica L. Hyperglycemia Homair
Content Type	Text

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