NDLI: Deep Eutectic Solvents (DESs) as Green Extraction Media of Beneficial Bioactive Phytochemicals

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Deep Eutectic Solvents (DESs) as Green Extraction Media of Beneficial Bioactive Phytochemicals

Content Provider	MDPI
Author	Dheyab, Ali Sami Bakar, Mohd Fadzelly Abu AlOmar, Mohamed Sabran, Siti Fatimah Hanafi, Ahmad Fathi Muhamad Mohamad, Azman
Copyright Year	2021
Description	Deep eutectic solvents (DES) are a mixture of two or more components and are classified as ionic solvents with special properties such as low volatility, high solubility, low melting points, low-cost materials and are less toxic to humans. Using DES has been suggested as an eco-friendly, green method for extraction of bioactive compounds from medicinal plants and are a safe alternative for nutritional, pharmaceutical and various sector applications. Conventional solvent extraction methods present drawbacks such as long extraction period, safety issues, harmful to the environment, costly and large volume of solvents required. The extraction method with DES leads to higher extraction yield and better bioactivity results as compared to the conventional solvents. This review provides a summary of research progress regarding the advantages of using DES to extract bioactive compounds such as phenolic acid, flavonoids, isoflavones, catechins, polysaccharides, curcuminoids, proanthocyanidin, phycocyanin, gingerols, ginsenosides, anthocyanin, xanthone, volatile monoterpenes, tannins, lignin, pectin, rutin, tert-butyl hydroquinone, chlorogenic acids, resveratrol and others, as opposed to using conventional solvents. The bioactivity of the extracts is determined using antioxidant, antibacterial and antitumor activities. Hence, DESs are considered potential green media with selective and efficient properties for extracting bioactive ingredients from medicinal plants.
Starting Page	176
e-ISSN	22978739
DOI	10.3390/separations8100176
Journal	Separations
Issue Number	10
Volume Number	8
Language	English
Publisher	MDPI
Publisher Date	2021-10-07
Access Restriction	Open
Subject Keyword	Separations Medicinal Plants Deep Eutectic Solvents Green Extraction Phytochemical Bioactivity
Content Type	Text
Resource Type	Article

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