NDLI: Defining Pre-Clinical Psoriatic Arthritis in an Integrated Dermato-Rheumatology Environment

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Defining Pre-Clinical Psoriatic Arthritis in an Integrated Dermato-Rheumatology Environment

Content Provider	MDPI
Author	Savage, Laura Tinazzi, Ilaria Zabotti, Alen Laws, Philip M. Wittmann, Miriam McGonagle, Dennis
Copyright Year	2020
Description	In excess of three quarters of patients with psoriatic arthritis (PsA) have preceding psoriasis (PsO), which offers a clinical biomarker for the recognition of early PsA. Numerous surveys have shown a remarkably high frequency of clinically occult musculoskeletal symptoms in psoriasis patients. Imaging studies, particularly ultrasound, show a high prevalence of subclinical enthesitis and other inflammatory changes in psoriasis subjects. Since a serum biomarker, such as the case of anti-citrullinated protein antibodies (ACPA) in rheumatoid arthritis, neither exists nor seems biologically plausible at this point, this article explores how integration of rheumatological and dermatological assessment can be facilitated for the early recognition of potential PsA. Given that scalp disease is a PsA predictor, but may be managed in the community, then a particular need to access this group is needed. An integrated approach between rheumatology and dermatology can involve joint clinics, parallel clinics with discussion of relevant cases or virtual contact between specialties. Early therapy evaluation and integrated strategies have considerable implications for minimizing suffering and joint damage in PsA.
Starting Page	3262
e-ISSN	20770383
DOI	10.3390/jcm9103262
Journal	Journal of clinical medicine
Issue Number	10
Volume Number	9
Language	English
Publisher	MDPI
Publisher Date	2020-10-12
Access Restriction	Open
Subject Keyword	Journal of clinical medicine Journal of Clinical Medicine Rheumatology Psoriasis Psoriatic Arthritis Integrated Dermato-rheumatology Clinic Psoriatic Arthralgia Pre-clinical Psoriatic Arthritis
Content Type	Text
Resource Type	Article

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