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Multi-Omic Biomarkers as Potential Tools for the Characterisation of Pancreatic Cystic Lesions and Cancer: Innovative Patient Data Integration
| Content Provider | MDPI |
|---|---|
| Author | Kane, Laura Mellotte, Gregory Conlon, Kevin Ryan, Barbara Maher, Stephen |
| Copyright Year | 2021 |
| Description | Pancreatic cancer (PC) is among the most aggressive types of cancer, having caused over 495,000 deaths worldwide in 2020, with increasing annual incidence. Pancreatic cystic lesions (PCLs) are protrusions found within or on the surface of the pancreas, and in many cases have the potential to become malignant. Current methods of characterising PCLs are imperfect and there is a profound need for improved diagnostic algorithms. This review highlights the importance of biological markers in the context of PCLs and PC, with a focus on ‘omics’-related work. Successful integration of different ‘omics’ data could aid in the identification of a novel integrated biomarker profile for the risk stratification of patients with PCLs and PC. |
| Starting Page | 769 |
| e-ISSN | 20726694 |
| DOI | 10.3390/cancers13040769 |
| Journal | Cancers |
| Issue Number | 4 |
| Volume Number | 13 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-02-12 |
| Access Restriction | Open |
| Subject Keyword | Cancers Oncology Pancreatic Cancer Pancreatic Cystic Lesion Biomarker Risk Omics Multi-omics |
| Content Type | Text |
| Resource Type | Article |
