NDLI: Acute Kidney Injury Recovery Patterns in ST-Segment Elevation Myocardial Infarction Patients

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Acute Kidney Injury Recovery Patterns in ST-Segment Elevation Myocardial Infarction Patients

Content Provider	MDPI
Author	Itach, Tamar Banai, Ariel Paran, Yael Zahler, David Merdler, Ilan Eliashiv, David Banai, Shmuel Shacham, Yacov
Copyright Year	2022
Description	Background: Acute kidney injury (AKI) is a frequent complication in patients with ST-segment elevation myocardial infarction (STEMI) undergoing percutaneous coronary intervention (PCI). Identification of different AKI recovery patterns may improve patient prognostic stratification. We investigated the clinical relevance of AKI recovery patterns among STEMI patients undergoing PCI. Methods: A retrospective study of 2943 STEMI patients undergoing PCI. The incidence of renal impairment, in-hospital complications, short and long-term mortality, were compared between patients without AKI, with early recovery defined as a return to baseline creatinine within 72 h, and no AKI recovery/delayed recovery defined as all other AKI cases. Results: A total of 255 (8.7%) patients developed AKI, of whom 124/255 (49%) patients had an early recovery, whereas 131/255 (51%) had no AKI recovery/delayed recovery. Patients without recovery were more likely to have in-hospital complications and higher long-term mortality (36.64% vs. 7.25%%; p < 0.001). In a multivariable regression model, the mortality hazard ratio (HR) for long term mortality remained significant for patients with no/delayed recovery AKI (HR 7.76, 95% CI 4.69 to 12.86, p < 0.001), and a strong trend among patients with resolving AKI (HR 2.09, 95% CI 0.933–4.687, p = 0.071). Conclusions: Among STEMI patients undergoing PCI, the recovery pattern of AKI is a valuable prognostic marker.
Starting Page	2169
e-ISSN	20770383
DOI	10.3390/jcm11082169
Journal	Journal of clinical medicine
Issue Number	8
Volume Number	11
Language	English
Publisher	MDPI
Publisher Date	2022-04-13
Access Restriction	Open
Subject Keyword	Journal of clinical medicine Journal of Clinical Medicine Peripheral Vascular Disease Acute Kidney Injury St-segment Elevation Myocardial Infarction Percutaneous Coronary Intervention Cardiac Intensive Care Unit
Content Type	Text
Resource Type	Article

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