NDLI: Cardiac Arrhythmias in Survivors of Sudden Cardiac Death Requiring Impella Assist Device Therapy

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Cardiac Arrhythmias in Survivors of Sudden Cardiac Death Requiring Impella Assist Device Therapy

Content Provider	MDPI
Author	Fabian, Föttinger Abdullah, Khaled Roedler, Jana Dahl, Juergen Vom Szendey, Istvan Dimitroulis, Dimitrios Eckardt, Lars Topf, Albert Ohnewein, Bernhard Fritsch, Lorenz Brandt, Mathias Wernly, Bernhard Motloch, Lukas Larbig, Robert
Copyright Year	2021
Description	In this retrospective single-center trial, we analyze 109 consecutive patients (female: 27.5%, median age: 69 years, median left ventricular ejection fraction: 20%) who survived sudden cardiac death (SCD) and needed hemodynamic support from an Impella assist device between 2008 and 2018. Rhythm monitoring is investigated in this population and associations with hospital survival are analyzed. Hospital mortality is high, at 83.5%. Diverse cardiac arrhythmias are frequently registered during Impella treatment. These include atrial fibrillation (AF, 21.1%) and ventricular tachycardia (VT, 18.3%), as well as AV block II°/III° (AVB, 7.3%), while intermittent asystole (ASY) is the most frequently observed arrhythmia (42.2%). Nevertheless, neither ventricular nor supraventricular tachycardias are associated with patients’ survival. In patients who experience intermittent asystole, a trend towards a fatal outcome is noted (p = 0.06). Conclusions: Mortality is high in these severely sick patients. While cardiac arrhythmias were frequent, they did not predict hospital mortality in this population. The hemodynamic support of the pump seems to counterbalance the adverse effects of these events.
Starting Page	1393
e-ISSN	20770383
DOI	10.3390/jcm10071393
Journal	Journal of clinical medicine
Issue Number	7
Volume Number	10
Language	English
Publisher	MDPI
Publisher Date	2021-03-31
Access Restriction	Open
Subject Keyword	Journal of clinical medicine Journal of Clinical Medicine Surgery Sudden Cardiac Death Impella Assist Devices Arrhythmias Asystole Ventricular Tachycardia Atrial Fibrillation
Content Type	Text
Resource Type	Article

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