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Defining Blood Plasma and Serum Metabolome by GC-MS
| Content Provider | MDPI |
|---|---|
| Author | Kiseleva, Olga Kurbatov, Ilya Ilgisonis, Ekaterina Poverennaya, Ekaterina |
| Copyright Year | 2021 |
| Description | Metabolomics uses advanced analytical chemistry methods to analyze metabolites in biological samples. The most intensively studied samples are blood and its liquid components: plasma and serum. Armed with advanced equipment and progressive software solutions, the scientific community has shown that small molecules’ roles in living systems are not limited to traditional “building blocks” or “just fuel” for cellular energy. As a result, the conclusions based on studying the metabolome are finding practical reflection in molecular medicine and a better understanding of fundamental biochemical processes in living systems. This review is not a detailed protocol of metabolomic analysis. However, it should support the reader with information about the achievements in the whole process of metabolic exploration of human plasma and serum using mass spectrometry combined with gas chromatography. |
| Starting Page | 15 |
| e-ISSN | 22181989 |
| DOI | 10.3390/metabo12010015 |
| Journal | Metabolites |
| Issue Number | 1 |
| Volume Number | 12 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-12-24 |
| Access Restriction | Open |
| Subject Keyword | Metabolites Biochemical Research Serum Plasma Metabolomics Gas Chromatography-mass Spectrometry (gc-ms) Multi-omics |
| Content Type | Text |
| Resource Type | Article |
