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Features of $PABIG^{nx}$ 3D Polymer Gel as an Ionising Radiation Dosimeter
| Content Provider | MDPI |
|---|---|
| Author | Kozicki, Marek Jaszczak, Malwina Maras, Piotr |
| Copyright Year | 2022 |
| Description | This work presents the features of the $PABIG^{nx}$ 3D polymer gel dosimeter. It consists of two cross-linkers: poly(ethylene glycol) diacrylate (PEGDA), as one biacrylic component, and N,N′-methylenebisacrylamide (MBA), which is another cross-linker often used in 3D dosimeters. Additionally, it contains oxygen scavenges of copper sulfate pentahydrate and ascorbic acid. All ingredients are embedded in a physical gel matrix of gelatine. Upon irradiation, the biacrylic cross-linking agents (PEGDA and MBA) undergo radical polymerisation and cross-linking, which is manifested by the appearance of the opacity of the intensity related to the absorbed dose. $PABIG^{nx}$ was irradiated with an oncological source of ionising radiation, and analysed by using a nuclear magnetic resonance (0.5 T). The following characteristics were obtained: (i) linear and dynamic dose-response of 0.5 to ~18 Gy and 40 Gy, respectively, (ii) dose sensitivity of 0.071 ± 0.001 $Gy^{−1}$ $s^{−1}$, (iii) integral 3D dose distribution for at least 24 days after irradiation, (iv) adequate batch-to-batch reproducibility, (v) dose-response independent of irradiation with 6 MV photons, 15 MV photons, 6 MV photons FFF of 0.0168–0.1094 Gy/s dose rates, and (vi) soft tissue equivalence. The study showed that the features of $PABIG^{nx}$ confirm its suitability for use in 3D radiotherapy dosimetry. |
| Starting Page | 2550 |
| e-ISSN | 19961944 |
| DOI | 10.3390/ma15072550 |
| Journal | Materials |
| Issue Number | 7 |
| Volume Number | 15 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-03-31 |
| Access Restriction | Open |
| Subject Keyword | Materials Radiology, Nuclear Medicine and Imaging Pabignx 3d Polymer Gel Dosimetry Radiotherapy Dosimetry Ionising Radiation |
| Content Type | Text |
| Resource Type | Article |