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Pathogenesis of the Pseudomonas aeruginosa Biofilm: A Review
| Content Provider | MDPI |
|---|---|
| Author | Tuon, Felipe Francisco Dantas, Leticia Ramos Suss, Paula Hansen Ribeiro, Victoria Stadler Tasca |
| Copyright Year | 2022 |
| Description | Pseudomonas aeruginosa is associated with several human infections, mainly related to healthcare services. In the hospital, it is associated with resistance to several antibiotics, which poses a great challenge to therapy. However, one of the biggest challenges in treating P. aeruginosa infections is that related to biofilms. The complex structure of the P. aeruginosa biofilm contributes an additional factor to the pathogenicity of this microorganism, leading to therapeutic failure, in addition to escape from the immune system, and generating chronic infections that are difficult to eradicate. In this review, we address several molecular aspects of the pathogenicity of P. aeruginosa biofilms. |
| Starting Page | 300 |
| e-ISSN | 20760817 |
| DOI | 10.3390/pathogens11030300 |
| Journal | Pathogens |
| Issue Number | 3 |
| Volume Number | 11 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-02-27 |
| Access Restriction | Open |
| Subject Keyword | Pathogens Pseudomonas Aeruginosa Biofilm Quorum Sensing Virulence |
| Content Type | Text |
| Resource Type | Article |
