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Multiple Endocrine Neoplasia in Childhood: An Update on Diagnosis, Screening, Management and Treatment
| Content Provider | MDPI |
|---|---|
| Author | Jacob, Marianne Rowland, Dustin Lekarev, Oksana Ergun-Longmire, Berrin |
| Copyright Year | 2022 |
| Description | Multiple endocrine neoplasia (MEN) is a group of heterogenous syndromes characterized by the occurrence of two or more endocrine gland tumors in a patient or related individuals in the same family. They are inherited in an autosomal dominant fashion and are highly penetrant. There are three types of MEN syndromes: MEN type 1 (MEN1), MEN type 2 (MEN2), and MEN type 4 (MEN4). MEN2 is further divided into MEN2A, MEN2B (formerly known MEN3), and familial medullary thyroid carcinoma (FMTC). Although MEN syndromes are rare, it is crucial to identify individuals at risk for potentially life-threatening neoplasias. This review article provides an update on each MEN syndrome, its genetics, diagnosis, and management in children. |
| Ending Page | 91 |
| Page Count | 16 |
| Starting Page | 76 |
| e-ISSN | 2673396X |
| DOI | 10.3390/endocrines3010007 |
| Journal | Endocrines |
| Issue Number | 1 |
| Volume Number | 3 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-02-17 |
| Access Restriction | Open |
| Subject Keyword | Endocrines Endocrinology and Metabolism Multiple Endocrine Neoplasia Men1 Men2a Men2b Men4 Familial Medullary Thyroid Carcinoma |
| Content Type | Text |
| Resource Type | Article |
