NDLI: Pre-Exposure Prophylaxis (PrEP) Adherence Questionnaire: Psychometric Validation among Sexually Transmitted Infection Patients in China

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Pre-Exposure Prophylaxis (PrEP) Adherence Questionnaire: Psychometric Validation among Sexually Transmitted Infection Patients in China

Content Provider	MDPI
Author	Yu, Xiaoyue Xu, Chen Ni, Yang Chang, Ruijie Wang, Huwen Gong, Ruijie Wang, Ying Wang, Suping Cai, Yong
Copyright Year	2021
Description	Background: Ensuring adherence guarantees the efficacy of pre-exposure prophylaxis (PrEP). Methods: We conducted a cross-sectional study among 816 sexually transmitted infection (STI) patients in Shanghai. The questionnaire included self-reported demographic characteristics, self-administered items on adherence to free oral PrEP, and PrEP uptake behavior measurement. We conducted item analysis, reliability analysis, validity analysis and receiver operating characteristic (ROC) curve analysis. Results: Not all items were considered acceptable in the item analysis. The questionnaire had a McDonald’s ω coefficient of 0.847. The scale-level content validity index (CVI) was 0.938 and the item-level CVI of each item ranged from 0.750 to 1. In exploratory factor analysis, we introduced a four-factor model accounting for 79.838% of the aggregate variance, which was validated in confirmatory factor analysis. Adding PrEP adherence questionnaire scores contributed to prediction of PrEP uptake behavior (p < 0.001) in regression analysis. The maximum area under the ROC curve was 0.778 (95% IC: 0.739–0.817). Conclusion: The PrEP adherence questionnaire presented psychometric validation among STI patients.
Starting Page	10980
e-ISSN	16604601
DOI	10.3390/ijerph182010980
Journal	International Journal of Environmental Research and Public Health
Issue Number	20
Volume Number	18
Language	English
Publisher	MDPI
Publisher Date	2021-10-19
Access Restriction	Open
Subject Keyword	International Journal of Environmental Research and Public Health Womens Studies Pre-exposure Prophylaxis (prep) Hiv Prevention Questionnaire Adherence
Content Type	Text
Resource Type	Article

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