NDLI: Challenges in the Diagnosis and Management of Fibrotic Hypersensitivity Pneumonitis: A Practical Review of Current Approaches

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Challenges in the Diagnosis and Management of Fibrotic Hypersensitivity Pneumonitis: A Practical Review of Current Approaches

Content Provider	MDPI
Author	Moua, Teng Petnak, Tananchai Charokopos, Antonios Baqir, Misbah Ryu, Jay H.
Copyright Year	2022
Description	Recent advances in fibrotic hypersensitivity pneumonitis include improved diagnostic guidance, systematic assessments of immunosuppressive therapy, and the recent availability of antifibrotic therapy (nintedanib) for those with progressive disease. A standardized approach to diagnosis may lead to better inclusion criteria for future therapeutic protocols and delineation of disease or treatment response predictors for real-world management. This review will highlight current diagnostic and treatment challenges and remaining knowledge gaps or areas of uncertainty, with a practical overview of supporting evidence and its clinical implications. Exposure history, serologic testing for antigen sensitivity, bronchoalveolar lavage lymphocytosis, histopathology, and radiologic findings will be covered in the diagnosis section, with immunosuppression, antifibrotic therapy, lung transplantation, and disease prognosis in the treatment and management section.
Starting Page	1473
e-ISSN	20770383
DOI	10.3390/jcm11061473
Journal	Journal of clinical medicine
Issue Number	6
Volume Number	11
Language	English
Publisher	MDPI
Publisher Date	2022-03-08
Access Restriction	Open
Subject Keyword	Journal of clinical medicine Journal of Clinical Medicine Urology and Nephrology Hypersensitivity Pneumonitis Lung Fibrosis Interstitial Lung Disease
Content Type	Text
Resource Type	Article

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