NDLI: Probiotic and Functional Properties of Limosilactobacillus reuteri INIA P572

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Probiotic and Functional Properties of Limosilactobacillus reuteri INIA P572

Content Provider	MDPI
Author	Izaskun, Martín-Cabrejas Laura, Hidalgo-García Ana, García-Lafuente Alba, Rodríguez-Nogales Mar, ía Rodríguez-Cabezas Julio, Gálvez Juan, Arqués Diez-Echave, Patricia Garrido-Mesa, José Langa, Susana Vezza, Teresa Landete, José Algieri, Francesca Mayer, Melinda Narbad, Arjan Medina, Margarita
Copyright Year	2021
Description	Limosilactobacillus reuteri INIA P572 is a strain able to produce the antimicrobial compound reuterin in dairy products, exhibiting a protective effect against some food-borne pathogens. In this study, we investigated some probiotic properties of this strain such as resistance to gastrointestinal passage or to colonic conditions, reuterin production in a colonic environment, and immunomodulatory activity, using different in vitro and in vivo models. The results showed a high resistance of this strain to gastrointestinal conditions, as well as capacity to grow and produce reuterin in a human colonic model. Although the in vitro assays using the RAW 264.7 macrophage cell line did not demonstrate direct immunomodulatory properties, the in vivo assays using a Dextran Sulphate Sodium (DSS)-induced colitic mice model showed clear immunomodulatory and protective effects of this strain.
Starting Page	1860
e-ISSN	20726643
DOI	10.3390/nu13061860
Journal	Nutrients
Issue Number	6
Volume Number	13
Language	English
Publisher	MDPI
Publisher Date	2021-05-29
Access Restriction	Open
Subject Keyword	Nutrients Food Science and Technology Limosilactobacillus Reuteri Probiotic Colonic Model Dss-induced Colitic Model Immunomodulation Reuterin Protective Effect
Content Type	Text
Resource Type	Article

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