NDLI: In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium

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In Vitro Biological Characterization of Silver-Doped Anodic Oxide Coating on Titanium

Content Provider	MDPI
Author	Alicja, Kazek-Kęsik Oleshko, Oleksandr Liubchak, Iryna Husak, Yevheniia Korniienko, Viktoriia Yusupova, Aziza Oleshko, Tetiana Banasiuk, Rafal Szkodo, Marek Matros-Taranets, Igor Simka, Wojciech Pogorielov, Maksym
Copyright Year	2020
Description	Despite the high biocompatibility and clinical effectiveness of Ti-based implants, surface functionalization (with complex osteointegrative/antibacterial strategies) is still required. To enhance the dental implant surface and to provide additional osteoinductive and antibacterial properties, plasma electrolytic oxidation of a pure Ti was performed using a nitrilotriacetic acid (NTA)-based Ag nanoparticles (AgNP)-loaded calcium–phosphate solution. Chemical and structural properties of the surface-modified titanium were assessed using scanning electron microscopy (SEM) with energy dispersive X-ray (EDX) and contact angle measurement. A bacterial adhesion test and cell culture biocompatibility with collagen production were performed to evaluate biological effectiveness of the Ti after the plasma electrolytic process. The NTA-based calcium–phosphate solution with Ag nanoparticles (AgNPs) can provide formation of a thick, porous plasma electrolytic oxidation (PEO) layer enriched in silver oxide. Voltage elevation leads to increased porosity and a hydrophilic nature of the newly formed ceramic coating. The silver-enriched PEO layer exhibits an effective antibacterial effect with high biocompatibility and increased collagen production that could be an effective complex strategy for dental and orthopedic implant development.
Starting Page	4359
e-ISSN	19961944
DOI	10.3390/ma13194359
Journal	Materials
Issue Number	19
Volume Number	13
Language	English
Publisher	MDPI
Publisher Date	2020-09-30
Access Restriction	Open
Subject Keyword	Materials Dentistry and Oral Surgery Plasma Electrolytic Oxidation Titanium Agnps Biocompatibility Antibacterial Coatings
Content Type	Text
Resource Type	Article

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