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COVID-19 Vaccine Acceptance among Low- and Lower-Middle-Income Countries: A Rapid Systematic Review and Meta-Analysis
| Content Provider | MDPI |
|---|---|
| Author | Patwary, Muhammad Mainuddin Alam, Ashraful Bardhan, Mondira Disha, Asma Safia Haque, Zahidul Billah, Sharif Mutasim Kabir, Pervez Browning, Matthew H. E. M. Rahman, Mizanur Parsa, Ali Davod Kabir, Russell |
| Copyright Year | 2022 |
| Description | Widespread vaccination against COVID-19 is critical for controlling the pandemic. Despite the development of safe and efficacious vaccinations, low-and lower-middle income countries (LMICs) continue to encounter barriers to care owing to inequitable access and vaccine apprehension. This study aimed to summarize the available data on COVID-19 vaccine acceptance rates and factors associated with acceptance in LMICs. A comprehensive search was performed in PubMed, Scopus, and Web of Science from inception through August 2021. Quality assessments of the included studies were carried out using the eight-item Joanna Briggs Institute Critical Appraisal tool for cross-sectional studies. We performed a meta-analysis to estimate pooled acceptance rates with 95% confidence intervals (CI). A total of 36 studies met the inclusion criteria and were included in the review. A total of 83,867 respondents from 33 countries were studied. Most of the studies were conducted in India (n = 9), Egypt (n = 6), Bangladesh (n = 4), or Nigeria (n = 4). The pooled-effect size of the COVID-19 vaccine acceptance rate was 58.5% (95% CI: 46.9, 69.7, $I^{2}$ = 100%, 33 studies) and the pooled vaccine hesitancy rate was 38.2% (95% CI: 27.2–49.7, $I^{2}$ = 100%, 32 studies). In country-specific sub-group analyses, India showed the highest rates of vaccine acceptancy (76.7%, 95% CI: 65.8–84.9%, $I^{2}$= 98%), while Egypt showed the lowest rates of vaccine acceptancy (42.6%, 95% CI: 16.6–73.5%, $I^{2}$= 98%). Being male and perceiving risk of COVID-19 infection were predictors for willingness to accept the vaccine. Increasing vaccine acceptance rates in the global south should be prioritized to advance global vaccination coverage. |
| Starting Page | 427 |
| e-ISSN | 2076393X |
| DOI | 10.3390/vaccines10030427 |
| Journal | Vaccines |
| Issue Number | 3 |
| Volume Number | 10 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2022-03-11 |
| Access Restriction | Open |
| Subject Keyword | Vaccines Biomedical Social Sciences Vaccine Hesitancy Vaccine Acceptance Covid-19 Low- and Lower-middle Income Countries Meta-analysis Sars-cov-2 Vaccine |
| Content Type | Text |
| Resource Type | Article |