NDLI: Nitric Oxide Signaling and Its Association with Ubiquitin-Mediated Proteasomal Degradation in Plants

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Nitric Oxide Signaling and Its Association with Ubiquitin-Mediated Proteasomal Degradation in Plants

Content Provider	MDPI
Author	Pande, Anjali Mun, Bong-Gyu Khan, Murtaza Rahim, Waqas Lee, Da-Sol Lee, Geun-Mo Azawi, Tiba Nazar Ibrahim Al Hussain, Adil Yun, Byung-Wook
Copyright Year	2022
Description	Nitric oxide (NO) is a versatile signaling molecule with diverse roles in plant biology. The NO-mediated signaling mechanism includes post-translational modifications (PTMs) of target proteins. There exists a close link between NO-mediated PTMs and the proteasomal degradation of proteins via ubiquitylation. In some cases, ubiquitin-mediated proteasomal degradation of target proteins is followed by an NO-mediated post-translational modification on them, while in other cases NO-mediated PTMs can regulate the ubiquitylation of the components of ubiquitin-mediated proteasomal machinery for promoting their activity. Another pathway that links NO signaling with the ubiquitin-mediated degradation of proteins is the N-degron pathway. Overall, these mechanisms reflect an important mechanism of NO signal perception and transduction that reflect a close association of NO signaling with proteasomal degradation via ubiquitylation. Therefore, this review provides insight into those pathways that link NO-PTMs with ubiquitylation.
Starting Page	1657
e-ISSN	14220067
DOI	10.3390/ijms23031657
Journal	International Journal of Molecular Sciences
Issue Number	3
Volume Number	23
Language	English
Publisher	MDPI
Publisher Date	2022-01-31
Access Restriction	Open
Subject Keyword	International Journal of Molecular Sciences Nitric Oxide Ubiquitylation S-nitrosylation Proteasome Proteolysis
Content Type	Text
Resource Type	Article

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