NDLI: Julbernardia paniculata and Pterocarpus angolensis: From Ethnobotanical Surveys to Phytochemical Characterization and Bioactivities Evaluation

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Julbernardia paniculata and Pterocarpus angolensis: From Ethnobotanical Surveys to Phytochemical Characterization and Bioactivities Evaluation

Content Provider	MDPI
Author	Joana, Gonçalves Luís, Ângelo Santos, Eugénia Solange Rosado, Tiago Pereira, Luísa Gallardo, Eugenia Duarte, Ana Paula
Copyright Year	2020
Description	Julbernardia paniculata and Pterocarpus angolensis are two plant species with important application in African traditional medicine, particularly in Angola, in the treatment of several diseases. However, scientific studies concerning these species are scarce. The goal of this work was to know better which medicinal approaches are used by the Huíla population in Angola by means of ethnobotanical surveys. Furthermore, extracts of both plants were phytochemically characterized. Antioxidant, anti-inflammatory, wound-healing activities, and potential cytotoxicity were also studied. With this study it was possible to verify that 67% of the individuals that use medicinal plants are women, and their main therapeutic uses are the treatment of problems of the digestive system and skin disorders. Barks of J. paniculata and leaves of P. angolensis are the most often used plant parts. Through high-performance liquid chromatography coupled to diode-array detector (HPLC-DAD) and GC-MS it was possible to characterize the chemical composition of the two species, which are rich in phenolic compounds, terpenes, terpenoids, sesquiterpenoids and fatty acids. Both plants showed to possess antioxidant, anti-inflammatory proprieties, and wound-healing activity. To the best of our knowledge, this is the most comprehensive study of these two species and the first ethnobotanical and ethnopharmacological study of medicinal plants from this region of Angola.
Starting Page	1828
e-ISSN	14203049
DOI	10.3390/molecules25081828
Journal	Molecules
Issue Number	8
Volume Number	25
Language	English
Publisher	MDPI
Publisher Date	2020-04-16
Access Restriction	Open
Subject Keyword	Molecules Integrative and Complementary Medicine Julbernardia Paniculata Pterocarpus Angolensis Ethnobotanical Surveys Hplc-dad Gc-ms Phytochemicals Wound-healing Activity
Content Type	Text
Resource Type	Article

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