Loading...
Please wait, while we are loading the content...
Similar Documents
Development of a Proton-Frequency-Transparent Birdcage Radiofrequency Coil for In Vivo$ ^{13}$C MRS/MRSI Study in a 3.0 T MRI System
| Content Provider | MDPI |
|---|---|
| Author | Yoon, Jun-Sik Kim, Jong-Min Chung, Han-Jae Jeong, You-Jin Jeong, Gwang-Woo Park, Ilwoo Kim, Gwang-Won Oh, Chang-Hyun |
| Copyright Year | 2021 |
| Description | A proton-frequency-transparent (PFT) birdcage RF coil that contains carbon-proton switching circuits (CPSCs) is presented to acquire$ ^{13}$C MR signals, which, in turn, enable$ ^{1}$H imaging with existing$ ^{1}$H RF coils without being affected by a transparent$ ^{13}$C birdcage RF coil. CPSCs were installed in the PFT$ ^{13}$C birdcage RF coil to cut the RF coil circuits during$ ^{1}$H MR imaging. Finite-difference time-domain (FDTD) electromagnetic (EM) simulations were performed to verify the performance of the proposed CPSCs. The performance of the PFT$ ^{13}$C birdcage RF coil with CPSCs was verified via phantom and in vivo MR studies. In the phantom MR studies,$ ^{1}$H MR images and$ ^{13}$C MR spectra were acquired and compared with each other using the$ ^{13}$C birdcage RF coil with and without the CPSCs. For the in vivo MR studies, hyperpolarized$ ^{13}$C cardiac MRS and MRSI of swine were performed. The proposed PFT$ ^{13}$C birdcage RF coil with CPSCs led to a percent image uniformity (PIU) reduction of 1.53% in the proton MR images when compared with the case without it. FDTD EM simulations revealed PIU reduction of 0.06% under the same conditions as the phantom MR studies. Furthermore, an SNR reduction of 5.5% was observed at$ ^{13}$C MR spectra of corn-oil phantom using the PFT$ ^{13}$C birdcage RF coil with CPSCs compared with that of the$ ^{13}$C birdcage RF coil without CPSCs. Utilizing the PFT$ ^{13}$C birdcage RF coil,$ ^{13}$C-enriched compounds were successfully acquired via in vivo hyperpolarized$ ^{13}$C MRS/MRSI experiments. In conclusion, the applicability and utility of the proposed 16-leg low-pass PFT$ ^{13}$C birdcage RF coil with CPSCs were verified via$ ^{1}$H MR imaging and hyperpolarized$ ^{13}$C MRS/MRSI studies using a 3.0 T MRI system. |
| Starting Page | 11445 |
| e-ISSN | 20763417 |
| DOI | 10.3390/app112311445 |
| Journal | Applied Sciences |
| Issue Number | 23 |
| Volume Number | 11 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-12-02 |
| Access Restriction | Open |
| Subject Keyword | Applied Sciences Radiology, Nuclear Medicine and Imaging Hyperpolarized Magnetic Resonance Imaging Birdcage Rf Coil Carbon-13 Magnetic Resonance Spectroscopic Imaging Slab Dynamic Mrs Free Induction Decay Chemical Shift Imaging |
| Content Type | Text |
| Resource Type | Article |
