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Myocarditis and Pericarditis Following mRNA COVID-19 Vaccination: What Do We Know So Far?
| Content Provider | MDPI |
|---|---|
| Author | Das, Bibhuti Moskowitz, William Taylor, Mary Palmer, April |
| Copyright Year | 2021 |
| Description | This is a cross-sectional study of 29 published cases of acute myopericarditis following COVID-19 mRNA vaccination. The most common presentation was chest pain within 1–5 days after the second dose of mRNA COVID-19 vaccination. All patients had an elevated troponin. Cardiac magnetic resonance imaging revealed late gadolinium enhancement consistent with myocarditis in 69% of cases. All patients recovered clinically rapidly within 1–3 weeks. Most patients were treated with non-steroidal anti-inflammatory drugs for symptomatic relief, and 4 received intravenous immune globulin and corticosteroids. We speculate a possible causal relationship between vaccine administration and myocarditis. The data from our analysis confirms that all myocarditis and pericarditis cases are mild and resolve within a few days to few weeks. The bottom line is that the risk of cardiac complications among children and adults due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection far exceeds the minimal and rare risks of vaccination-related transient myocardial or pericardial inflammation. |
| Starting Page | 607 |
| e-ISSN | 22279067 |
| DOI | 10.3390/children8070607 |
| Journal | Children |
| Issue Number | 7 |
| Volume Number | 8 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-07-18 |
| Access Restriction | Open |
| Subject Keyword | Children Infectious Diseases Covid-19 Vaccine Myocarditis Pericarditis |
| Content Type | Text |
| Resource Type | Article |
