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Enamel Remineralization Competence of a Novel Fluoride-Incorporated Bioactive Glass Toothpaste—A Surface Micro-Hardness, Profilometric, and Micro-Computed Tomographic Analysis
| Content Provider | MDPI |
|---|---|
| Author | Farooq, Imran Ali, Saqib Farooqi, Faraz Ahmed AlHumaid, Jehan Binhasan, Mashael Shabib, Sara Vohra, Fahim Abduljabbar, Tariq |
| Copyright Year | 2021 |
| Description | This study aimed to analyze the enamel remineralization efficacy of a novel fluoridated bioactive glass (F-BG) toothpaste compared to a standard fluoride toothpaste. Seventy-two enamel blocks (N = 72) were divided into groups of twenty-four blocks according to the toothpaste exposure—group 1: brushed with distilled water, group 2: brushed with fluoride toothpaste $(Colgate^{TM}$), and group 3: brushed with F-BG toothpaste $(BioMinF^{TM}$). Pre-brushing, enamel blocks were demineralized using 6 wt.% citric acid (pH = 2.4). Tooth brushing was performed using a mixture of respective toothpaste and artificial saliva (AS), and each enamel block received 5000 linear strokes. The samples were assessed for surface micro-hardness (to estimate Vickers hardness number, VHN), surface roughness (Ra), and volume loss/gain using micro-computed tomography (micro-CT). The highest increase in the VHN was noticed for group 3 (117.81) followed by group 2 (61.13), and all the intragroup comparisons were statistically significant (p < 0.05). Demineralization increased the Ra values, and a decrease was observed post-remineralization for all the groups. The maximum Ra decrease was observed for group 3 (−223.2 nm) followed by group 2 (−55.6 nm), and all the intragroup comparisons were again statistically significant (p < 0.05). Micro-CT investigation revealed that the enamel volume decreased after demineralization and increased after remineralization among all groups. The F-BG toothpaste showed greater enamel surface micro-hardness (increased VHN), smoother surface (low roughness), and better volume restoration (remineralization) in comparison to the fluoride toothpaste. |
| Ending Page | 766 |
| Page Count | 15 |
| Starting Page | 752 |
| e-ISSN | 2379139X |
| DOI | 10.3390/tomography7040063 |
| Journal | Tomography |
| Issue Number | 4 |
| Volume Number | 7 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-11-09 |
| Access Restriction | Open |
| Subject Keyword | Tomography Dentistry and Oral Surgery Dental Enamel Bioactive Glass Fluoride Toothpaste Surface Micro-hardness Surface Roughness Micro-ct |
| Content Type | Text |
| Resource Type | Article |
