NDLI: Functionalization of Electrospun Nanofiber for Bone Tissue Engineering

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Functionalization of Electrospun Nanofiber for Bone Tissue Engineering

Content Provider	MDPI
Author	Yan, Xuan Yao, Haiyan Luo, Jun Li, Zhihua Wei, Junchao
Copyright Year	2022
Description	Bone-tissue engineering is an alternative treatment for bone defects with great potential in which scaffold is a critical factor to determine the effect of bone regeneration. Electrospun nanofibers are widely used as scaffolds in the biomedical field for their similarity with the structure of the extracellular matrix (ECM). Their unique characteristics are: larger surface areas, porosity and processability; these make them ideal candidates for bone-tissue engineering. This review briefly introduces bone-tissue engineering and summarizes the materials and methods for electrospining. More importantly, how to functionalize electrospun nanofibers to make them more conducive for bone regeneration is highlighted. Finally, the existing deficiencies of functionalized electrospun nanofibers for promoting osteogenesis are proposed. Such a summary can lay the foundation for the clinical practice of functionalized electrospun nanofibers.
Starting Page	2940
e-ISSN	20734360
DOI	10.3390/polym14142940
Journal	Polymers
Issue Number	14
Volume Number	14
Language	English
Publisher	MDPI
Publisher Date	2022-07-20
Access Restriction	Open
Subject Keyword	Polymers Electrospun Nanofiber Bone-tissue Engineering Functionalization Scaffold Bone Regeneration
Content Type	Text
Resource Type	Article

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