NDLI: The Diagnosis of Autoimmune Pancreatitis Using Endoscopic Ultrasonography

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The Diagnosis of Autoimmune Pancreatitis Using Endoscopic Ultrasonography

Content Provider	MDPI
Author	Kanno, Atsushi Ikeda, Eriko Ando, Kozue Nagai, Hiroki Miwata, Tetsuro Kawasaki, Yuki Tada, Yamato Yokoyama, Kensuke Numao, Norikatsu Ushio, Jun Tamada, Kiichi Lefor, Alan Kawarai Yamamoto, Hironori
Copyright Year	2020
Description	Autoimmune pancreatitis (AIP) is characterized by enlargement of the pancreas and irregular narrowing of the main pancreatic duct. It is often associated with IgG4-related sclerosing cholangitis (IgG4-SC), in which the bile duct narrows. Although characteristic irregular narrowing of the pancreatic duct caused by endoscopic retrograde cholangiopancreatography is noted in AIP, it is difficult to differentiate between localized AIP and pancreatic carcinoma based on imaging of the pancreatic duct. While stenosis of the bile duct in IgG4-SC is characterized by longer-length stenosis than in cholangiocarcinoma, differentiation based on bile duct imaging alone is challenging. Endoscopic ultrasound (EUS) can characterize hypoechoic enlargement of the pancreas or bile duct wall thickening in AIP and IgG4-SC, and diagnosis using elastography and contrast-enhanced EUS are being evaluated. The utility of EUS-guided fine needle aspiration for the histological diagnosis of AIP has been reported and is expected to improve diagnostic performance for AIP. Findings in the bile duct wall from endoscopic retrograde cholangiopancreatography followed by intraductal ultrasonography are useful in differentiating IgG4-SC from cholangiocarcinoma. Diagnoses based on endoscopic ultrasonography play a central role in the diagnosis of AIP.
Starting Page	1005
e-ISSN	20754418
DOI	10.3390/diagnostics10121005
Journal	Diagnostics
Issue Number	12
Volume Number	10
Language	English
Publisher	MDPI
Publisher Date	2020-11-25
Access Restriction	Open
Subject Keyword	Diagnostics Gastroenterology and Hepatology Autoimmune Pancreatitis (aip) Endoscopic Ultrasound (eus) Eus-guided Fine Needle Aspiration (eus-fna) Eus-guided Fine Needle Biopsy (eus-fnb) International Consensus Diagnostic Criteria (icdc)
Content Type	Text
Resource Type	Article

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