NDLI: Evaluation of the Bond Strength and Cytotoxicity of Alkasite Restorative Material

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Evaluation of the Bond Strength and Cytotoxicity of Alkasite Restorative Material

Content Provider	MDPI
Author	Awad, Mohamed Alshehri, Turki Alqarni, Ahmed Magdy, Nashaat Alhalabi, Feras Alotaibi, Dalal Alrahlah, Ali
Copyright Year	2020
Description	Cention N (CN; Ivoclar Vivadent, Schaan, Liechtenstein), advertised as an alkasite, is a bioactive bulk-fill resin-based composite (BF-RBC) with alkaline fillers. This study evaluated the resin-dentin micro-tensile bond strength (μTBS) and cytotoxicity of CN. Methods: Flat dentin surfaces were obtained, bonded with a universal adhesive, and randomly distributed into two groups. CN (group I) and a flowable BF-RBC, namely, Tetric N-Flow Bulk Fill, Ivoclar Vivadent, Schaan, Liechtenstein (group II), were used. After thermocycling, bonded samples were sectioned into micro-beams for μTBS evaluation. Resin-based composite (RBC) discs with a thickness of 2 and 4 mm were tested on human gingival fibroblast cells (HGFCs). Cytotoxicity was assessed by cell viability and growth using AlamarBlue® (Biosource, Camarillo, CA, USA) over a seven-day period. Independent t-test was utilized to statistically analyze μTBS data, while one- and two-way analysis of variance (ANOVA) and Tukey’s post-hoc tests were utilized to analyze the cell viability data. Results: There was no statistically significant difference (p > 0.05) in the μTBS between the flowable BF-RBC and CN. For both materials, the HGFCs were viable, with constant growing over the seven-day period. Conclusion: CN provided a resin-dentin μTBS that was comparable to that provided by the flowable BF-RBC. Both materials showed acceptable cytotoxicity over the seven-day period at a thickness of both 2 and 4 mm.
Starting Page	6175
e-ISSN	20763417
DOI	10.3390/app10186175
Journal	Applied Sciences
Issue Number	18
Volume Number	10
Language	English
Publisher	MDPI
Publisher Date	2020-09-04
Access Restriction	Open
Subject Keyword	Applied Sciences Dentistry and Oral Surgery Alkasite Bulk-fill Resin-based Composite Micro-tensile Bond Strength Dentin Cytotoxicity
Content Type	Text
Resource Type	Article

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