NDLI: The Complete Genome of Probiotic Lactobacillus sakei Derived from Plateau Yak Feces

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The Complete Genome of Probiotic Lactobacillus sakei Derived from Plateau Yak Feces

Content Provider	MDPI
Author	Li, Kun Liu, Juanjuan Zeng, Zhibo Kulyar, Muhammad Fakhar-E-Alam Wang, Yaping Li, Aoyun Bhutta, Zeeshan Ahmad Aqib, Amjad Islam Shahzad, Muhammad Li, Jiakui Qi, Desheng
Copyright Year	2020
Description	Probiotic bacteria are receiving increased attention due to the potential benefits to their hosts. Plateau yaks have resistance against diseases and stress, which is potentially related to their inner probiotics. To uncover the potential functional genes of yak probiotics, we sequenced the whole genome of Lactobacillus sakei (L. sakei). The results showed that the genome length of L. sakei was 1.99 Mbp, with 1943 protein coding genes (21 rRNA, 65 tRNA, and 1 tmRNA). There were three plasmids found in this bacteria, with 88 protein coding genes. EggNOG annotation uncovered that the L. sakei genes were found to belong to J (translation, ribosomal structure, and biogenesis), L (replication, recombination, and repair), G (carbohydrate transport and metabolism), and K (transcription). GO annotation showed that most of the L. sakei genes were related to cellular processes, metabolic processes, biological regulation, localization, response to stimulus, and organization or biogenesis of cellular components. CAZy annotation found that there were 123 CAZys in the L. sakei genome, with glycosyl transferases and glycoside hydrolases. Our results revealed the genome characteristics of L. sakei, which may give insight into the future employment of this probiotic bacterium for its functional benefits.
Starting Page	1527
e-ISSN	20734425
DOI	10.3390/genes11121527
Journal	Genes
Issue Number	12
Volume Number	11
Language	English
Publisher	MDPI
Publisher Date	2020-12-21
Access Restriction	Open
Subject Keyword	Genes Biochemical Research Probiotic Yak Lactobacillus Sakei Genome Sequencing
Content Type	Text
Resource Type	Article

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