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Clinical Usefulness of Ultrasound-Guided Fine Needle Aspiration and Core Needle Biopsy for Patients with Axillary Lymphadenopathy
| Content Provider | MDPI |
|---|---|
| Author | Fujioka, Tomoyuki Mori, Mio Kubota, Kazunori Yamaga, Emi Yashima, Yuka Oda, Goshi Nakagawa, Tsuyoshi Onishi, Iichiroh Ishiba, Toshiyuki Tateishi, Ukihide |
| Copyright Year | 2021 |
| Description | Background and Objectives: It is necessary to properly diagnose and manage axillary lymphadenopathy caused by a variety of diseases. This study aimed to evaluate the utility of ultrasound (US)-guided sampling in patients with axillary lymphadenopathy. Materials and Methods: Patients with axillary lymphadenopathy (excluding patients with newly diagnosed breast cancer) who underwent US-guided fine needle aspiration (FNA) or core needle biopsy (CNB) at a single center between February 2016 and September 2020 were retrospectively examined. The association between US imaging findings and malignancy was investigated and the diagnostic performance of US-guided sampling was assessed. Results: Fifty-five patients (including eight males) were included in the study; of these, 34 patients (61.8%) were finally diagnosed with a malignant lymph node lesion. Twenty-two patients (40.0%) had undergone FNA and 33 (60.0%) had undergone CNB. Larger short and long axis diameters, thicker lymph node cortex, and the absence of fatty hilum on the US were significantly associated with malignancy (p < 0.05). The diagnostic performance of FNA, CNB, and FNA + CNB was excellent (sensitivity, specificity, and accuracy of 0.909, 0.900, and 0.917 for FNA, 0.958, 1.000, and 0.970 for CNB, and 0.941, 0.952, and 0.945 for FNA + CNB, respectively). Conclusions: US-guided FNA and CNB play an important role in the diagnosis and management of patients with axillary lymphadenopathy. |
| Starting Page | 722 |
| e-ISSN | 16489144 |
| DOI | 10.3390/medicina57070722 |
| Journal | Medicina |
| Issue Number | 7 |
| Volume Number | 57 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-07-16 |
| Access Restriction | Open |
| Subject Keyword | Medicina Integrative and Complementary Medicine Ultrasound Core Needle Biopsy Fine Needle Aspiration Axillary Lymph Nodes Lymphadenopathy |
| Content Type | Text |
| Resource Type | Article |