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SEM/EDS Evaluation of the Mineral Deposition on a Polymeric Composite Resin of a Toothpaste Containing Biomimetic Zn-Carbonate Hydroxyapatite $(microRepair^{®}$) in Oral Environment: A Randomized Clinical Trial
| Content Provider | MDPI |
|---|---|
| Author | Butera, Andrea Pascadopoli, Maurizio Gallo, Simone Lelli, Marco Tarterini, Fabrizio Giglia, Federico Scribante, Andrea |
| Copyright Year | 2021 |
| Description | Toothpastes containing biomimetic hydroxyapatite have been investigated in recent years; the behavior of this material in the oral environment has been evaluated directly on dental enamel showing a marked remineralizing activity. To propose $microRepair^{®}$-based toothpastes (Zn-carbonate hydroxyapatite) for the domiciliary oral hygiene in patients with dental composite restorations, the aim of this study was to evaluate the deposition of Zn-carbonate hydroxyapatite on a polymeric composite resin with Scanning Electron Microscopy/Energy-Dispersive X-ray Spectrometry (SEM/EDS) analysis. Twenty healthy volunteers underwent the bonding of 3 orthodontic buttons on the vestibular surfaces of upper right premolars and first molar. On the surface of the buttons, a ball-shaped mass of composite resin was applied and light-cured. Then, the volunteers were randomly divided into two groups according to the toothpaste used for domiciliary oral hygiene: the Control toothpaste containing stannous fluoride and the Trial toothpaste containing $microRepair^{®}$. The buttons were debonded after 7 days (T1—first premolar), after 15 days (T2—second premolar), and after 30 days (T3—first molar) to undergo the SEM/EDS analysis. The deposition of calcium, phosphorus, and silicon was assessed through EDS analysis and data were submitted to statistical analysis (p < 0.05). SEM morphologic evaluation showed a marked deposition of the two toothpastes on the surfaces of the buttons. EDS quantitative analysis showed an increase of calcium, phosphorus, and silicon in both the groups, with a statistically significant difference of calcium deposition at T3 for the Trial group. Therefore, the use of toothpaste containing Zn-carbonate hydroxyapatite could be proposed as a device for domiciliary oral hygiene because the deposition of hydroxyapatite on polymeric composite resin could prevent secondary caries on the margins of restorations. |
| Starting Page | 2740 |
| e-ISSN | 20734360 |
| DOI | 10.3390/polym13162740 |
| Journal | Polymers |
| Issue Number | 16 |
| Volume Number | 13 |
| Language | English |
| Publisher | MDPI |
| Publisher Date | 2021-08-16 |
| Access Restriction | Open |
| Subject Keyword | Polymers Dentistry and Oral Surgery Biomimetic Dentistry Hydroxyapatite Microrepair Toothpaste Composite Resin Polymer Composite Mineral Deposition Remineralization Sem Eds |
| Content Type | Text |
| Resource Type | Article |